Results 41 to 50 of about 5,010,058 (349)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Haversian canal structures can be associated with size effects in cortical bone [PDF]
, 2012 Prediction of periprosthetic failure may be improved by an improved model of bone elasticity which includes microstructural information. Micropolar theory facilitates such information to be included in a continuum model.
Frame, Jamie Campbell +2 more
core
Question of quantum equivalence between Jordan frame and Einstein frame
, 2015 In the framework of a general scalar-tensor theory, we investigate the equivalence between two different parametrizations of fields that are commonly used in cosmology - the so-called Jordan frame and Einstein frame.
Kamenshchik, Alexander Yu. +1 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
mSystemsA recent study by A. Bhosle, M. I. Jackson, A. M. Walsh, E. A. Franzosa, et al. (mSystems 10:e00452-24, 2024, https://doi.org/10.1128/msystems.00452-24) enhances our understanding of dietary fiber’s impact on the gut microbiome and metabolome in ...
Leigh A. Frame
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Frontiers in Global Women's HealthBackgroundMaternal mortality in Ghana remains high at 263 deaths per 100,000 live births, with the Volta Region showing particularly concerning figures; 37.2% of women give birth without a skilled provider. Many rely on Traditional Birth Attendants (TBAs)
Sandrina Koppitz +3 more
doaj +1 more source
Lightweight bamboo structures - Report on 2021 International Collaboration on Bamboo Construction
Sustainable Structures, 2023 2021 International Collaboration on Bamboo Construction was held from September 1 to December 1, 2021. The practice was held by the College of Civil Engineering of Nanjing Forestry University, University College London, International Bamboo and Rattan ...
Assima Dauletbek +9 more
doaj +1 more source
On more than two decades of Celestial Reference Frame VLBI observations in the deep south: IVS-CRDS (1995–2021) [PDF]
, 2023 Stuart Weston +15 more
openalex +1 more source