Results 51 to 60 of about 5,010,058 (349)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
MULTIAGENT APPROACH FOR MANAGING THE INFORMATION SPACE OF CORPORATE SYSTEMS
The subject matter of the study is the integration and management of information resources of distributed computing corporate systems within the common information space.
Valentin Filatov, Valerii Semenets
doaj +1 more source
Scalable frames are frames with the property that the frame vectors can be rescaled resulting in tight frames. However, if a frame is not scalable, one has to aim for an approximate procedure. For this, in this paper we introduce three novel quantitative
Chen, Xuemei +4 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
De l'expression du point de vue à l'anticipation textuelle : le rôle de à première vue
We propose a semantic and pragmatic analysis of the french locution à première vue (lit. “at first sight”) when it indicates a point of view (in the sense of Nølke, 1994) and plays a role in textual structuration (Charolles, 1997).
Véronique Lenepveu
doaj +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
More than 20% of American adults live with a mental disorder, many of whom are treatment resistant or continue to experience symptoms. Other approaches are needed to improve mental health care, including prevention. The role of the microbiome has emerged
Alison Warren +3 more
doaj +1 more source
Less Oedipus, more Telemachus: the framing of fatherhood in international press
The aim of this article is to present an analysis of the image of the father of the family in four newspapers: The New York Times, Corriere della Sera, Gazeta Wyborcza and Rzeczpospolita. The study is not limited to examining what is explicitly presented
Piotr Studnicki
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source

