Results 51 to 60 of about 93,836 (268)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
El pluralismo polarizado ante la nueva política y el columnismo digital
El modelo de pluralismo polarizado del sistema mediático español se caracteriza por un periodismo ideológicamente alineado con los principales partidos políticos.
Adolfo Carratalá, Lidia Valera-Ordaz
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Proceedings of the 2nd Annual Meeting of the Berkeley Linguistics Society (1976), pp.
openaire +3 more sources
A Palestinian State - Yes or No? Constructing political discourse in the Israeli print news media - An experimental design [PDF]
This paper describes a research project which examines how attitudes are shaped and formed and how opinion makers and agenda setters influence such attitudes in their followers. We concentrate on the written media as our research environment.
Samuel Peleg, Eithan Alimi
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
We examined how the goal of a decision task influences the perceived positive, negative valence of the alternatives and thereby the likelihood and direction of framing effects. In Study 1 we manipulated the goal to increase, decrease or maintain the commodity in question and found that when the goal of the task was to increase the commodity, a framing ...
Todd McElroy, John J. Seta
openaire +1 more source
Scheduling Multipacket Frames with Frame Deadlines [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lukasz Jez +2 more
openaire +2 more sources
Responsibility judgments of wins and losses in the 2013 chess championship
We report two studies on the perceived responsibility of opponents competing for a goal that can be attained by only one of them. Responsibility judgments were collected in seven samples of lay people and experts before, during, and after the World Chess
Gro Hege Haraldsen Nordbye +1 more
doaj +1 more source

