Results 51 to 60 of about 4,247,451 (374)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Kvinder, Køn & ForskningDuring the 2010s, video game content and subsets of the gaming community have been diverging in polarized directions regarding LGBTQ topics in video game culture.
Kim S. P. Minuva
doaj +1 more source
Animals, 2018 In various contexts, people talk about animal farming and meat consumption using different arguments to construct and justify their (non-)acceptability.
Hanneke J. Nijland +2 more
doaj +1 more source
Ceiling-Floor Partition Separation: What Is It and Why Is It Occurring? [PDF]
, 1989 This publication is intended to increase the understanding of cracking or separation of finish materials occasionally found in light-frame wood construction. In many cases, the problem is caused by shrinking or swelling of the wood framing members due to
Percival, Donald H.
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Application of industrialised building system in school project in Malaysia: the challenge [PDF]
, 2013 Industrialised Building System (IBS) is a system that used prefabricated components manufactured in the factory using highly skilled workers and heavy machinery.
Mohd. Aizad, Johari
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Vaksinasi COVID-19 dan Polemik Raffi Ahmad dalam Framing Pemberitaan Media Tirto.id dan Detik.com
Calathu, 2021 This study aims to analyze how the media Tirto.id and Detik.com frame the violation of Raffi Ahmad's health protocol after receiving the first batch of Covid-19 vaccinations, using the framing analysis approach developed by Robert N. Entman. The concept
Khumaid Akhyat Sulkhan
doaj +1 more source
Abelian Chern-Simons theory, Stokes' theorem, and generalized connections
, 2011 Generalized connections and their calculus have been developed in the context of quantum gravity. Here we apply them to abelian Chern-Simons theory. We derive the expectation values of holonomies in U(1) Chern-Simons theory using Stokes' theorem, flux ...
Sahlmann, Hanno, Thiemann, Thomas
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source