Results 51 to 60 of about 68,413 (298)
Bracketing effects on risk tolerance: Generalizability and underlying mechanisms
Judgment and Decision Making, 2010 Research has shown that risk tolerance increases when multiple decisions and associated outcomes are presented together in a broader “bracket” rather than one at a time.
Ester Moher, Derek J. Koehler
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Individual sensitivity to framing effects [PDF]
, 2011 Surveys are sometimes viewed with suspicion when used to provide economic values, since they are sensitive to framing effects. However, the extent to which those effects may vary between individuals has received little attention.
Flachaire, Emmanuel, Hollard, Guillaume
core +2 more sources
Future Intention to disclose personal information via mobile apps
Revista de Ciências da Administração : RCA, 2021 This study analyses the future intention to disclose personal information in order to use mobile applications (apps) and the framing effect in relation to privacy concerns.
Sady Darcy da Silva Junior +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Frontiers in Psychology, 2018 This study assessed the extent to which within-individual variation in schizotypy and paranormal belief influenced performance on probabilistic reasoning tasks.
Andrew Denovan +3 more
doaj +1 more source
Public Support for Transport Reform: Does it Matter if we ‘Reduce Driving’ or ‘Shift Trips’?
Findings, 2021 Does what the public says they want in terms of transport policy depend on how we ask? In other words, are transportation policy preferences subject to framing effects?
Kelcie Ralph +3 more
doaj +1 more source
, 2010 Through the use of experimental methods, this study examines the claim that strategic news engenders political cynicism. Firstly, it builds upon previous theory by conceptualising and measuring political cynicism at both issue-specific and global levels.
Jackson, Dan, Dan Jackson
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source