Results 51 to 60 of about 31,947 (248)

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

International Journal of Cancer, EarlyView.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat, Francesco Cecere, Federica Rossetti, Laura Pignata, Emilia D'Angelo, Carlo Giaccari, Gaetano Verde, Paola Quarello, Franca Fagioli, Josep Roma, Manel Esteller, Enrique de Álava, Flavia Cerrato, Andrea Riccio, Angela Sparago   +14 more
wiley   +1 more source

Iatrogenic cerebral amyloid angiopathy: Two case reports to explore clinical heterogeneity and pathological patterns

Journal of Stroke and Cerebrovascular Diseases
Introduction: These case reports illustrate Iatrogenic Cerebral Amyloid Angiopathy (iCAA) due to neurosurgical procedures. Recent studies propose prion transmission during neurosurgery as a potential mechanism for β-amyloid seed implantation, linking ...
Carla Vera-Cáceres, MD, Nerses Nersesyan, MD, Maria Obon, MD, Ph.D, Mikel Terceño, MD, Ph.D, Joaquin Serena, MD, Ph.D, Juan Álvarez-Cienfuegos, MD, Tomàs Xuclà, MD, Saima Bashir, MD, Yolanda Silva, MD, Ph.D   +8 more
doaj   +1 more source

Dual Genotoxic and Antigenotoxic Effects of 3‐Benzoylcoumarins in Mammalian Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Coumarins are phenolic compounds widely recognized for their diverse pharmacological activities and have attracted increasing attention as potential chemopreventive agents. In the present study, four known 3‐benzoylcoumarin derivatives [(1), (2), (3), and (4)] were evaluated for their cytotoxic, mutagenic, and antigenotoxic effects in Chinese ...
Leticia Helena Parreira, Evelyn Pinheiro de Mendonça, Aléxia Polo Siqueira, Cleydson Finotti Cordeiro, Elkin José Torres Sierra, Rudy Bonfilio, Diogo Teixeira Carvalho, Pollyanna Francielli de Oliveira   +7 more
wiley   +1 more source

Low‐Dose Chlorothalonil Induces Testicular Injury Through Disruption of Steroidogenic Signaling in Adult Male Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorothalonil (CHL) is a widely used organochlorine fungicide frequently detected in environmental and food matrices. Although increasing evidence indicates adverse effects in nontarget species, the mechanisms underlying CHL‐induced male reproductive toxicity remain incompletely understood.
Cristiana Livramento Oliveira Pinto, Nicoly Caixêta Gonçalves, Paula Rafaela Queiroz da Silva, Ludmila Rodrigues Pontes, Juliana Reis Machado, Virmondes Rodrigues Jr., Hugo Felix Perini, Gláucia Eloisa Munhoz de Lion Siervo   +7 more
wiley   +1 more source

The Role of Online Support Groups in the Management of Trichotillomania Symptoms

Journal of Clinical Psychology, EarlyView.
ABSTRACT Background Many individuals with trichotillomania find themselves unable to access effective treatment and are forced to manage symptoms independently. Support groups play an important role in symptom management. Aims This qualitative study aimed to explore experiences with online support groups among hair‐pulling individuals (N = 20; 10 women,
Dan Jenkins, Rizwana Roomaney
wiley   +1 more source

A Morphological Study of Restoration of Damaged Hair Fiber With Chemical Treatments Using Microscopy Techniques

Microscopy Research and Technique, EarlyView.
Assessment of Restoring Chemically Damaged Hair Fibers Using Microscopy and Spectroscopy. ABSTRACT This paper analyses hair restoration products currently on the market that treat chemically processed hair. This study measured the restoration of structural integrity in hair samples from both chemically damaged hair (chemically relaxed, bleached, and ...
L. P. A. Mauricio, R. A. D. Cunha, S. M. Alves   +2 more
wiley   +1 more source

O RECONHECIMENTO E A EXECUÇÃO DE DECISÕES JUDICIAIS ESTRANGEIRAS NO BRASIL E O CASO DAS SENTENÇAS FRONTEIRIÇAS

Revista Eletrônica Direito e Política, 2008
Para chegar a uma efetiva cooperação judicial internacional entre Estados, onde vige o princípio da livre circulação dos julgados, é imprescindível a adoção de regras comuns que regulem a matéria, principalmente quando se trata de um espaço integrado ...
Carolina Gomes Chiappini, Luciane Klein Vieira   +1 more
doaj   +1 more source

Abdominal pain in pediatric immunoglobulin A vasculitis: Risk factors and severity predictors in a multicenter cohort

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To identify risk factors for abdominal pain and predictors of complicated abdominal pain in pediatric immunoglobulin A vasculitis (IgAV). Methods Retrospective multicenter study including children and adolescents (≤18 years) fulfilling the European League Against Rheumatism/Pediatric Rheumatology International Trials Organization ...
Francisco Hugo Rodrigues Gomes, Natalia Maronese, Leticia Lizardo Magalhaes, Davi Casale Aragon, Gleice Clemente, Maria Teresa Terreri, Claudio Arnaldo Len, Rozana Gasparello de Almeida, Marta Cristine Felix Rodrigues, Flavio Sztajnbok, Lia Vineyard Steuer, Matheus Santos França, Clovis Artur Almeida da Silva, Virginia Paes Leme Ferriani, Luciana Martins de Carvalho   +14 more
wiley   +1 more source

C‐LENS: An Integrative Process Framework for Managing Governance and Complexity in University–Industry Collaboration

Knowledge and Process Management, EarlyView.
ABSTRACT University–industry collaboration (UIC) often underperforms not because its relevance is unclear, but because collaboration processes are rarely designed to accommodate evolving governance needs amid complexity. Existing studies have examined drivers, barriers, and institutional interfaces, yet process dynamics, governance mechanisms, and ...
Carlos Alexandre Ferreira Gama, Monica Ferreira da Silva, Juliana Baptista dos Santos França, Adriana Santarosa Vivacqua   +3 more
wiley   +1 more source

Por uma economia histórica

Revista de História, 1953
(Primeiro Parágrafo do Artigo) Os resultados adquiridos pelas pesquisas de história econômica já são bastante densos para que nos seja lícito irmo para frente, pelo menos em pensamento, e de deduzir-mos, além, dos casos particulares, regras que aflitam
Fernand Braudel
doaj   +1 more source