Results 101 to 110 of about 4,086,452 (310)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Ticaret Mecmuasına Göre Suriye’nin İktisadi Yapısına Genel Bir Bakış 1925
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2019 25 Nisan 1922 Milletler Cemiyeti’nin 22. Maddesine göre, 28 Nisan 1919 da kurulan mandat sistemine dayanarak Suriye ve onun bir bölümü olarak tanımlanan Lübnan, “A” türü manda Yamaç, 2018:1157 olarak Fransa’ya verilmiştir.
Gülin Öztürk, Aslıhan Nakiboğlu
doaj
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
IMF Staff Country Reports, 1999 In recent years, the IMF has released a growing number of reports and other documents covering economic and financial developments and trends in member countries. Each report, prepared by a staff team after discussions with government officials, is published at the option of the member country.
openaire +2 more sources
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Osmanlı Diplomasisinde “Musalahalar Devletler İledür” Kaidesi
Gazi Akademik Bakış, 2020 It is not possible to think of the experience of the Ottoman Empire in the field of Diplomacy apart from her adventure in the field of politics. Just as her political adventure was in a unique way, her experience in the field of diplomacy was likewise ...
Hilal ÇİFTÇİ
doaj
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Storia e Politica, 2020 Henri Lacordaire was a leading figure in the history of Nineteenth-Century French Liberal-Catholicism. He aroused wide interest in the early years of the July Monarchy as an influential preacher in the Cathedral of Notre-Dame de Paris.
Mario Tesini
doaj
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Mitral valve endocardiosis in Cavalier King Charles spaniels in France: epidemiological, clinical and echo-Doppler study of 451 cases [PDF]
, 2004 A retrospective study was performed in the Cardiology Unit of Alfort in 451 Cavalier King Charles (CKC) spaniels. A left apical systolic murmur was detected in 183 of them (40.6 %). The prevalence of the murmur increased with age (18.8 %
TISSIER, Renaud +15 more
core +1 more source