Results 81 to 90 of about 4,086,452 (310)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Identification of Borna disease virus in France

open access: yes, 2000
La maladie de Boma, surtout connue depuis le 17' siècle en Allemagne chez les chevaux, est une affection émergente pour d’autres espèces animales et l’homme.
Bode, Lise   +3 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Anti-CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non-Active Multiple Sclerosis. [PDF]

open access: yesAnn Clin Transl Neurol
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Moukhine A   +40 more
europepmc   +2 more sources

Varroosis and others honey bee diseases : major causes for colony mortality in France [PDF]

open access: yes, 2008
Various investigations carried out in France since 1987 have shown the correlation between winter mortality and diseases in bees. In 2008, very high mortality rates are back despite the removal from the market of the systemic ...
CHAUZAT, Marie-Pierre   +5 more
core   +1 more source

Dynamiques d'intégration des espaces naturels protégés en France : une approche comparative entre parcs nationaux et réserves naturelles

open access: yesNatures Sciences Sociétés, 2017
Ces trente dernières années, les espaces naturels protégés (ENP) ont connu un changement majeur de paradigme, des approches ségrégatives aux approches intégratives.
Cosson Arnaud   +4 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Influence of the Un Formation Process to the Establishment of the XX Century World Order

open access: yesУправленческое консультирование, 2018
This article presents a review and analysis of discussion of several questions that gave rise for some deep controversies during the United Nations Conference on International Organization. The United Nations Conference on International Organization held
Dmitry Guennadievich Novik
doaj  

Filaroidosis infection in an immunocompetent adult dog from France

open access: yesHelminthologia, 2018
A dog from Paris (France) was referred with a 2-week history of dry cough, intermittent acute onset of dyspnoea, and acute abdominal pain. A generalised bronchoalveolar infiltrate with a patchy distribution was observed at chest x-rays and computed ...
Cervone M.   +4 more
doaj   +1 more source

Approches anticipées et planifiées de la compensation écologique en Allemagne : vers un retour d’expérience pour la France ? [PDF]

open access: yesSciences, Eaux & Territoires, 2020
Les organisations planifiées et mutualisées de la compensation apparaissent dès la fin des années 1990 en Allemagne, soit plus de dix ans avant que la France n’adopte elle-même de telles approches.
BAS, Adeline   +6 more
doaj  

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