Results 61 to 70 of about 1,446,866 (269)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Influence of the Un Formation Process to the Establishment of the XX Century World Order
Управленческое консультирование, 2018 This article presents a review and analysis of discussion of several questions that gave rise for some deep controversies during the United Nations Conference on International Organization. The United Nations Conference on International Organization held
Dmitry Guennadievich Novik
doaj
Natures Sciences Sociétés, 2017 Ces trente dernières années, les espaces naturels protégés (ENP) ont connu un changement majeur de paradigme, des approches ségrégatives aux approches intégratives.
Cosson Arnaud +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Filaroidosis infection in an immunocompetent adult dog from France
Helminthologia, 2018 A dog from Paris (France) was referred with a 2-week history of dry cough, intermittent acute onset of dyspnoea, and acute abdominal pain. A generalised bronchoalveolar infiltrate with a patchy distribution was observed at chest x-rays and computed ...
Cervone M. +4 more
doaj +1 more source
Approches anticipées et planifiées de la compensation écologique en Allemagne : vers un retour d’expérience pour la France ? [PDF]
Sciences, Eaux & Territoires, 2020 Les organisations planifiées et mutualisées de la compensation apparaissent dès la fin des années 1990 en Allemagne, soit plus de dix ans avant que la France n’adopte elle-même de telles approches.
BAS, Adeline +6 more
doaj
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Ecology and Society, 2019 Even if agroecology and ecosystem services are multidimensional framework concepts, recognizing the technical, social, and ecological dimensions of agriculture, they have developed from different traditions (conservation biology for ecosystem services ...
Xavier Arnauld de Sartre +2 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Brief history of Chinese medicine in France
Chinese Medicine and Culture, 2018 In the 17th century, Chinese medicine appeared in France; since then, it never stopped evolving and is applied by French practitioners. Today, acupuncture is widely used in clinic treatment in France.
Marc Mezard
doaj +1 more source