Results 41 to 50 of about 3,789,803 (310)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Discours scientifique et littérature. Approche de la citation chez Martin Winckler [PDF]

open access: yesParole Rubate, 2014
This article examines the function of quotation in two novels by Martin Winckler. Referring to Antoine Compagnon's critical suggestions, I have tried to distinguish between the function of long quotations and shorter ones.
Fabienne Gooset
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Historical approach to rural youth (nineteenth century France)

open access: yesMemoria y Civilización, 2011
This article outlines an analysis of the situation and the role of youth in nineteenth century rural France. Socially well integrated, they are perceived as the lifeblood of rural communities, which they attributed a number of tasks in the organization ...
Jean-Claude Farcy
doaj  

Le paleoenvironnement vegetal des occupations humaines de la Grotte de Payre à la fin du Pleistocène moyen et au début du Pleistocène supérieur (Ardèche, France)

open access: yesTrabajos de Prehistoria, 2001
[es] El emplazamiento arqueológico del Paleolítico Medio de Payre se sitúa al sureste de Francia, en el valle del Ródano, en el contexto mediterráneo actual.
Chafika Kalai   +2 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

The influence of environmental variables on the distribution of diatom communities in an alpine proglacial stream, Taillon-Babiétous catchment, french Pyrénées

open access: yesPirineos: Revista de Ecología de Montaña, 2004
[fr] Bien que les algues soient d'importants composants des écosystèmes des eaux courantes, leur distribution dans les torrents de montagne a été peu étudiée.
L. E. Brown   +4 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy