Results 71 to 80 of about 4,086,452 (310)
Natures Sciences Sociétés, 2020 Les incitations croissantes à l’interdisciplinarité viennent modifier les pratiques de recherche dès le doctorat. Les doctorants faisant le choix de l’interdisciplinarité peuvent se trouver livrés à eux-mêmes face aux défis méthodologiques et ...
Chassé Pierre +2 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Pathogens identified in calves with neonatal gastro-enteritis in Vendée (France) [PDF]
, 2006 The object of this study was to describe the relative involvement of major pathogens in neonatal gastroenteritis in calves less than one month of age in Vendée (France). One to four samples of faeces from affected calves were collected in
Ogier de Beaulny, Myriam +13 more
core +1 more source
La fascistizzazione dei migranti italiani in Francia e Brasile: una comparazione
Storicamente, 2018 The aim of this paper is to compare the process of fascist penetration in the Italian immigrant communities of Brazil and France. Through the fasci italiani all’estero and the Organizzazione Nazionale Dopolavoro’s sections, the fascistization
Pietro Pinna
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Health monitoring of wildlife in France : SAGIR network and epidemiological monitoring of chiroptera rabies [PDF]
, 2006 Two wildlife surveillance networks centralised at AFSSA-LERRPAS are presented. SAGIR network is a generalist network monitoring wildlife diseases in France.
Florence Cliquet +12 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Le rôle des professeurs du Collège de France dans la création de l’EPHE
, 2020 Céline Surprenant, « Le rôle des professeurs du Collège de France dans la création de l’EPHE », dans J.-L. Fournet (dir.), Ma grande église et ma petite chapelle.
Surprenant, Céline
core +1 more source
French EEZs in the Pacific in the context of ocean change
Lex Portus, 2020 France is present in the Pacific region via its overseas collectivities being French Polynesia, New Caledonia, and Wallis & Futuna. This geostrategic region is also called the Blue Pacific bearing in mind its enormous maritime areas in comparison to the ...
Joanna Siekiera
doaj +1 more source