Results 131 to 140 of about 3,198,103 (279)

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

open access: yesAdvanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang   +7 more
wiley   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

open access: yesAdvanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li   +9 more
wiley   +1 more source

Ecología integral. Una lectura de Laudato Si' desde el capitalismo neoliberal

open access: yesMiscelánea Comillas, 2017
La propuesta del Papa Francisco en Laudato Si’ va más allá de incorporar las preocupaciones medioambientales a la Doctrina Social de la Iglesia. Francisco realiza un fino análisis de los problemas globales que afectan a la humanidad y descubre que hay ...
Bernardo Pérez Andreo
doaj  

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

open access: yesAdvanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao   +16 more
wiley   +1 more source

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

open access: yesAdvanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin   +10 more
wiley   +1 more source

A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model

open access: yesAdvanced Science, EarlyView.
We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren   +6 more
wiley   +1 more source

How Halide Segregation Governs the Ion Density Evolution and Ionic Performance Losses: From Degradation to Recovery

open access: yesAdvanced Energy Materials, EarlyView.
Halide segregation (HS) in mixed‐halide wide‐bandgap (WBG) perovskites is key to the stability of perovskite‐based tandem cells and a central focus of large‐scale research efforts. Here, we find that the underlying reason for the poor stability of cells prone to HS is enhanced ionic losses during operation. Furthermore, we identified irreversible ionic
Nikhil Kalasariya   +24 more
wiley   +1 more source

Estamos provavelmente no teatro

open access: yesSinais de Cena, 2008
Crítica de Rui Pina Coelho ao espectáculo, Shadow Play / Jogo Sombra, da autoria de Maila Dimas, Susana Nunes, Carlos Marques e Francisco Campos na versão e encenação de Francisco Campos, 2008.
Rui Pina Coelho
doaj  

Insight‐Guided Optimization of the Individual Steps in Ambient Slot‐Die‐Coated Perovskite Solar Cells

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This graphical abstract presents an integrated workflow for optimizing perovskite thin film fabrication by tuning ink rheology, refining processing parameters, and controlling crystallization. Viscosity control and process optimization precisely regulate wet film thickness and drying time, while crystallization directed by solvent additives yields ...
Alejandra Flórez   +8 more
wiley   +1 more source

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