Results 191 to 200 of about 5,449 (210)

Thermodynamic Stabilization of Human Frataxin

2023
ABSTRACT Recombinant proteins and antibodies are routinely used as drugs to treat prevalent diseases such as diabetes or cancer, while enzyme replacement and gene therapies are the main therapeutic intervention lines in rare diseases. In protein-based therapeutics, optimized in vivo
Reyes Núñez-Franco, Angel Torres-Mozas, Claudio D. Navo, Andreas Schedlbauer, Mikel Azkargorta, Ibon Iloro, Félix Elortza, Gabriel Ortega, Oscar Millet, Francesca Peccati, Gonzalo Jiménez-Osés   +10 more
openaire   +1 more source

The frataxin story

Neuromuscular Disorders, 1997
Victoria Campuzano, Hana Koutnikova, Françoise Foury, Mireille Cossée, Ornella Cazzalini, Michel Koenig   +5 more
openaire   +1 more source

Waiting for frataxin

Nature Genetics, 1997
Joseph V. Gray, Keith J. Johnson
openaire   +1 more source

Frataxin controls ketone body metabolism through regulation of OXCT1

PNAS Nexus, 2022
Yi Na Dong, Elizabeth Mercado-Ayon, Nathan Warren   +2 more
exaly  

Oxidative stress-dependent frataxin inhibition mediated alcoholic hepatocytotoxicity through ferroptosis

Toxicology, 2020
Xiaoping Guo, Hongkun Lin, Chunjie Jiang   +2 more
exaly  

High Levels of Frataxin Overexpression Lead to Mitochondrial and Cardiac Toxicity in Mouse Models

Molecular Therapy - Methods and Clinical Development, 2020
Hélène Puccio
exaly  

Iron‐induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo

EMBO Reports, 2004
Kerman Aloria, Brenda Schilke, Elizabeth A Craig   +2 more
exaly  

Frataxin

2008
openaire   +1 more source

Deficiency of Arabidopsis thaliana frataxin alters activity of mitochondrial Fe-S proteins and induces oxidative stress

Plant Journal, 2006
Maria V Busi, Hugo A Valdez, Eduardo Zabaleta   +2 more
exaly  

Nitric oxide accumulation is required to protect against iron‐mediated oxidative stress in frataxin‐deficient Arabidopsis plants

FEBS Letters, 2009
Diego F Gómez-Casati, Lorenzo Lamattina, Eduardo Zabaleta   +2 more
exaly