Results 1 to 10 of about 5,631 (165)

Traditional clinical risk factors outperform disease activity and hematologic indices for FRAX hip fracture risk in rheumatoid arthritis [PDF]

open access: yesFrontiers in Immunology
BackgroundHip fractures are among the most devastating complications of osteoporosis, yet determinants of the Fracture Risk Assessment Tool (FRAX)–estimated 10-year hip fracture probability (FRAX-Hip) in rheumatoid arthritis (RA) remain incompletely ...
Lina Zhang   +4 more
doaj   +2 more sources

A brief history of FRAX [PDF]

open access: yesArchives of Osteoporosis, 2018
This paper reviews the research programme that went into the development of FRAX® and its impact in the 10 years since its release in 2008.Osteoporosis is defined on the measurement of bone mineral density though the clinical consequence is fracture.
J A Kanis   +2 more
exaly   +5 more sources

FRAX Update

open access: yesJournal of Clinical Densitometry, 2017
The fracture risk assessment tool, FRAX, was released in 2008 and provides country-specific algorithms for estimating individualized 10-year probability of hip and major osteoporotic fracture (hip, clinical spine, distal forearm, and proximal humerus).
J A Kanis   +2 more
exaly   +5 more sources

Worldwide uptake of FRAX

open access: yesArchives of Osteoporosis, 2014
The worldwide uptake of FRAX is described.The aim of this report was to determine the usage of FRAX worldwide over a 1-year period from 1 May 2012.The number of FRAX calculations from each country was assessed over a 1-year period and expressed as calculations per million of the population aged 50 years or more. Countries were colour coded according to
J A Kanis, H Johansson, A ODÉN
exaly   +5 more sources

Underestimation of fracture risk by conventional FRAX thresholds in axial spondyloarthritis: a proposal for disease-specific thresholds [PDF]

open access: yesTherapeutic Advances in Musculoskeletal Disease
Background: The Fracture Risk Assessment Tool (FRAX) is widely used as an intervention threshold for postmenopausal osteoporosis but has not been validated specifically for axial spondyloarthritis (axSpA).
Sumapa Chaiamnuay, Apiwit Harirattanakul
doaj   +2 more sources

Low Predictive Value of FRAX Adjusted by Trabecular Bone Score for Osteoporotic Fractures in Korean Women: A Community-Based Cohort Study [PDF]

open access: yesEndocrinology and Metabolism, 2020
Background The value of the Fracture Risk Assessment Tool (FRAX) and the trabecular bone score (TBS) for assessing osteoporotic fracture risk has not been fully elucidated in Koreans.
Hana Kim   +8 more
doaj   +1 more source

FRAX and ethnicity [PDF]

open access: yesOsteoporosis International, 2020
[Extract] In the case of osteoporosis and FRAX, the authors do not appear to have grasped the reality of fracture epidemiology and risk assessment. In this editorial, we set out the key messages from the epidemiology of fracture globally, key considerations in building risk assessment tools, the specific contribution of race/ethnicity and practical ...
Kanis, J. A.   +9 more
openaire   +8 more sources

Comparison of Trabecular Bone Score–Adjusted Fracture Risk Assessment (TBS-FRAX) and FRAX Tools for Identification of High Fracture Risk among Taiwanese Adults Aged 50 to 90 Years with or without Prediabetes and Diabetes

open access: yesMedicina, 2022
Background and Objectives: The burden of osteoporosis is projected to increase. Identification and prompt intervention for osteoporotic fractures are important.
Tzyy-Ling Chuang   +3 more
doaj   +1 more source

Rational formulation engineering of fraxinellone utilizing 6-O-α-D-maltosyl-β-cyclodextrin for enhanced oral bioavailability and hepatic fibrosis therapy

open access: yesDrug Delivery, 2021
Although Fraxinellone (Frax) isolated from Dictamnus albus L. possessed excellent anti-hepatic fibrosis activity, oral administration of Frax suffered from the inefficient therapeutic outcome in vivo due to negligible oral absorption.
Jianbo Li   +8 more
doaj   +1 more source

FRAX in Haemodialysis Patients: Preliminary Results

open access: yesActa Clinica Croatica, 2021
The incidence of bone fractures is several times higher in haemodialysis (HD) patients than in the general population. FRAX is a fracture risk evaluation tool and shows a 10-year probability of bone fracture.
Draško Pavlović   +5 more
doaj   +1 more source

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