Results 1 to 10 of about 5,665 (183)

Traditional clinical risk factors outperform disease activity and hematologic indices for FRAX hip fracture risk in rheumatoid arthritis [PDF]

Frontiers in Immunology
BackgroundHip fractures are among the most devastating complications of osteoporosis, yet determinants of the Fracture Risk Assessment Tool (FRAX)–estimated 10-year hip fracture probability (FRAX-Hip) in rheumatoid arthritis (RA) remain incompletely ...
Lina Zhang, Yuwei Wang, Xin Li, Sheng-Guang Li, Di Jin   +4 more
doaj   +2 more sources

Underestimation of fracture risk by conventional FRAX thresholds in axial spondyloarthritis: a proposal for disease-specific thresholds [PDF]

Therapeutic Advances in Musculoskeletal Disease
Background: The Fracture Risk Assessment Tool (FRAX) is widely used as an intervention threshold for postmenopausal osteoporosis but has not been validated specifically for axial spondyloarthritis (axSpA).
Sumapa Chaiamnuay, Apiwit Harirattanakul
doaj   +2 more sources

Potential Extensions of the US FRAX Algorithm [PDF]

Journal of Osteoporosis, 2012
To determine if the revised US FRAX can identify those at high risk for fractures at any skeletal site, we studied 250 women and 249 men ≥40 years old from an age-stratified random sample of Rochester, MN residents.
L. Joseph Melton, Elizabeth J. Atkinson, Sara J. Achenbach, John A. Kanis, Terry M. Therneau, Helena Johansson, Sundeep Khosla, Shreyasee Amin   +7 more
doaj   +5 more sources

Low Predictive Value of FRAX Adjusted by Trabecular Bone Score for Osteoporotic Fractures in Korean Women: A Community-Based Cohort Study [PDF]

Endocrinology and Metabolism, 2020
Background The value of the Fracture Risk Assessment Tool (FRAX) and the trabecular bone score (TBS) for assessing osteoporotic fracture risk has not been fully elucidated in Koreans.
Hana Kim, Jung Hee Kim, Min Joo Kim, A Ram Hong, HyungJin Choi, EuJeong Ku, Ji Hyun Lee, Chan Soo Shin, Nam H. Cho   +8 more
doaj   +1 more source

FRAX and ethnicity [PDF]

Osteoporosis International, 2020
[Extract] In the case of osteoporosis and FRAX, the authors do not appear to have grasped the reality of fracture epidemiology and risk assessment. In this editorial, we set out the key messages from the epidemiology of fracture globally, key considerations in building risk assessment tools, the specific contribution of race/ethnicity and practical ...
Kanis, J. A., Cooper, C., Dawson-Hughes, B., Harvey, N. C., Johansson, H., Lorentzon, M., McCloskey, E. V., Reginster, J.-Y., Rizzoli, René, International Osteoporosis Foundation   +9 more
openaire   +8 more sources

Comparison of Trabecular Bone Score–Adjusted Fracture Risk Assessment (TBS-FRAX) and FRAX Tools for Identification of High Fracture Risk among Taiwanese Adults Aged 50 to 90 Years with or without Prediabetes and Diabetes

Medicina, 2022
Background and Objectives: The burden of osteoporosis is projected to increase. Identification and prompt intervention for osteoporotic fractures are important.
Tzyy-Ling Chuang, Mei-Hua Chuang, Yuh-Feng Wang, Malcolm Koo   +3 more
doaj   +1 more source

Rational formulation engineering of fraxinellone utilizing 6-O-α-D-maltosyl-β-cyclodextrin for enhanced oral bioavailability and hepatic fibrosis therapy

Drug Delivery, 2021
Although Fraxinellone (Frax) isolated from Dictamnus albus L. possessed excellent anti-hepatic fibrosis activity, oral administration of Frax suffered from the inefficient therapeutic outcome in vivo due to negligible oral absorption.
Jianbo Li, Tiange Feng, Weijing Yang, Yaru Xu, Shuaishuai Wang, Huijie Cai, Zhilei Liu, Hong Qiang, Jinjie Zhang   +8 more
doaj   +1 more source

FRAX in Haemodialysis Patients: Preliminary Results

Acta Clinica Croatica, 2021
The incidence of bone fractures is several times higher in haemodialysis (HD) patients than in the general population. FRAX is a fracture risk evaluation tool and shows a 10-year probability of bone fracture.
Draško Pavlović, Sonja Dits, Dijana Knežević Strinavić, Slava Doko, Ivančica Hršak, Boris Kudumija   +5 more
doaj   +1 more source

Risk of osteoporotic fracture in women using the FRAX tool with and without bone mineral density score in patients followed at a tertiary outpatient clinic ‒ An observational study

Clinics, 2022
Objectives: Fragility fractures increase morbidity and mortality. Adding assessment of clinical risk factors independently or as a previous step to Bone Densitometry (BD) should provide better accuracy in fracture risk prediction. FRAX tool might be used
Maria Helena Sampaio Favarato, Maria Flora de Almeida, Arnaldo Lichtenstein, Milton de Arruda Martins, Mario Ferreira Junior   +4 more
doaj   +1 more source

P142 Fracture risk in diabetes: to FRAX or not to FRAX?

Rheumatology, 2022
Abstract Background/Aims Diabetes mellitus is associated with decreased bone strength as well as increased fracture risk. The risk of fragility fracture increases with an increase in the duration of diabetes and worsening of glycemic control.
Mekha Mathew, Shivangi Dwivedi, Harit Buch, Srinivasan Venkatachalam   +3 more
openaire   +1 more source