Results 91 to 100 of about 10,859 (260)

Screening for Osteoporosis in Nonagenarians: A Scoping Review

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 12, Page 3870-3883, December 2025.
ABSTRACT Background As the United States population continues to age and advancements contribute to enhanced life expectancy, care for nonagenarians (adults aged 90 years and older) is as important as ever. A prominent concern within healthcare for the oldest old remains the occurrence of fragility fractures, and subsequent 1‐year mortality, making ...
Hannah A. Mosher   +4 more
wiley   +1 more source

Application of the World Health Organization Fracture Risk Assessment Tool to predict need for dual-energy X-ray absorptiometry scanning in postmenopausal women

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2015
Objective: To evaluate the efficacy of the World Health Organization Fracture Risk Assessment Tool, excluding bone mineral density (pre-BMD FRAX), in identifying Taiwanese postmenopausal women needing dual-energy X-ray absorptiometry (DXA) examination ...
An-Shine Chao   +5 more
doaj   +1 more source

Polygenic Risk Score as a Predictor of Bone Fracture or Osteoporosis in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

open access: yesCancer Medicine, Volume 14, Issue 22, November 2025.
ABSTRACT Background The association between single nucleotide polymorphisms (SNPs) and fracture risk has been established in various studies. Androgen‐deprivation therapy (ADT) for prostate cancer, while extending survival, increases the risk of osteoporosis and bone fracture.
Ying‐Qiang Liu   +6 more
wiley   +1 more source

Warming benefits to sheep fescue are negated by nearby plants and moss–lichen layers facilitate mycorrhizae in a tundra

open access: yesEcosphere, Volume 16, Issue 11, November 2025.
Abstract In systems where low temperatures limit plant productivity, facilitative effects of surrounding vegetation on juvenile plants may outweigh effects of competition for resources. This facilitation could occur through temperature buffering but also via increased availability of root mutualists such as mycorrhizal fungi.
Grace Rose Gutiérrez   +2 more
wiley   +1 more source

Artificial intelligence algorithms in orthopaedics: A narrative review of methods and clinical applications

open access: yesJournal of Experimental Orthopaedics, Volume 12, Issue 4, October 2025.
Artificial intelligence (AI) algorithms are transforming orthopaedics through imaging and outcome prediction, but safe clinical translation requires robust validation, transparent reporting and effective governance. Abstract This narrative review evaluates the role of artificial intelligence (AI) algorithms in orthopaedic surgery and distinguishes ...
Jamie Rosen   +3 more
wiley   +1 more source

Ocena 10-letniego ryzyka złamań u kobiet po menopauzie z wykorzystaniem algorytmu FRAX™, znormalizowanego dla populacji Włoch, Hiszpanii i Wielkiej Brytanii

open access: yesMenopause Review, 2010
Introduction: Taking into consideration the growing incidence of osteoporotic fractures, identification of patientswith the highest fracture risk seems to be the most rational and cost-effective solution of this clinical problem.The fracture risk ...
Elżbieta Skowrońska-Jóźwiak   +3 more
doaj  

Assessing fracture risk in early stage breast cancer patients treated with aromatase-inhibitors: An enhanced screening approach incorporating trabecular bone score

open access: yesJournal of Bone Oncology, 2017
Introduction: Aromatase-inhibitors (AIs) are commonly used for treatment of patients with hormone-receptor positive breast carcinoma, and are known to induce bone density loss and increase the risk of fractures.
Veronica Mariotti   +9 more
doaj   +1 more source

The FRAX®: critical appraisal

open access: yesInternational Journal of Clinical Rheumatology, 2009
The threshold for pharmacological intervention in osteoporosis remains controversial. Tools predicting the future risk of new fractures are increasingly used to establish a convenient individual risk:benefit ratio for a long-term treatment. The Fracture Risk Assessment Tool (FRAX®) is likely to become the most widely used tool for assessing fracture ...
openaire   +2 more sources

Epigenetic Clocks as Biomarkers for Bone Aging: Evidence From a Twin Study

open access: yesAging Cell, Volume 24, Issue 10, October 2025.
We investigated whether individuals with osteoporosis or fragility fracture are biologically older, as determined by the epigenetic clocks (biomarkers of aging). As the first of its kind, the study suggests that individuals with osteoporosis or fragility fractures exhibit accelerated aging based on their biological age determined by the epigenetic ...
Mette Soerensen   +3 more
wiley   +1 more source

Silent Dangers in Elderly Pharmacotherapy: The Interplay of Polypharmacy, Multimorbidity, and Drug Interactions

open access: yesJournal of Evaluation in Clinical Practice, Volume 31, Issue 7, October 2025.
ABSTRACT Background Pharmacological therapy in older persons is inherently complex due to the interplay of age‐related physiological changes, multimorbidity, and polypharmacy. These factors increase the vulnerability of elderly patients to drug interactions and adverse drug reactions.
N. N. Ngcobo
wiley   +1 more source

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