Results 71 to 80 of about 5,665 (183)
Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin +2 more
wiley +1 more source
Introduction: Taking into consideration the growing incidence of osteoporotic fractures, identification of patientswith the highest fracture risk seems to be the most rational and cost-effective solution of this clinical problem.The fracture risk ...
Elżbieta Skowrońska-Jóźwiak +3 more
doaj
Introduction: Aromatase-inhibitors (AIs) are commonly used for treatment of patients with hormone-receptor positive breast carcinoma, and are known to induce bone density loss and increase the risk of fractures.
Veronica Mariotti +9 more
doaj +1 more source
Zihan Fan, Xiaoyu Li, Xiaodong Zhang, Yong Yang, Qi Fei, Ai Guo Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Qi Fei; Ai GuoDepartment of Orthopedics, Beijing ...
Fan Z +5 more
doaj
Pitfalls in the external validation of FRAX
Recent studies have evaluated the performance of FRAX® in independent cohorts. The interpretation of most is problematic for reasons summarised in this perspective.FRAX is an extensively validated assessment tool for the prediction of fracture in men and women.
Kanis, John A. +3 more
openaire +4 more sources
Background. Vertebral fractures are one of the severe complications of systemic osteoporosis, which lead to the low-back pain, decrease or loss of efficiency and increase of mortality in older people.
N.V. Grygorieva, V.V. Povoroznyuk
doaj +1 more source
Objective: to evaluate bone tissue remodeling and mineral metabolism in elderly women who have not been previously examined and have received no antiosteoporotic therapy. Patients and methods.
S B Malichenko +4 more
doaj +1 more source
German DVO risk score identified more patients requiring treatment compared to FRAX
Purpose: Fracture risk determination is essential when recommending treatment in osteoporosis management. We calculated the risk probabilities of major osteoporotic and hip fractures using the DVO score established in German-speaking countries and the ...
Anna Frank +5 more
doaj +1 more source
The impact of GE Lunar vs ICMR database in diagnosis of osteoporosis among South Indian subjects
Objective: To study the effect of choosing ICMR reference values on the classification of bone mineral density in Indian patients. Design: Retrospective analysis of Dual Energy X-ray absorptiometry (DEXA) and clinical data.
Karthik Balachandran +2 more
doaj +1 more source

