Results 51 to 60 of about 7,915 (216)

Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum

Arthritis &Rheumatology, EarlyView.
Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig, David Jenkinson, James Bailey, Samantha Hider, Ian C. Scott, Sara Muller   +5 more
wiley   +1 more source

The impact of a FRAX-based intervention threshold in Turkey: the FRAX-TURK study

Archives of Osteoporosis, 2012
With the development of country-specific FRAX® tools to estimate fracture probability, guidance is required on the fracture probability at which treatment can be recommended.The aim of the present study was to determine FRAX-based intervention thresholds in men and women from Turkey and determine their population impact.Intervention thresholds for ...
Tuzun, Sansin, Eskiyurt, Nurten, Akarirmak, Ulku, Saridogan, Merih, Johansson, Helena, McCloskey, Eugene, Kanis, John A., Turkish Osteoporosis Society,, Turkish Osteoporosis Society   +8 more
openaire   +5 more sources

The Relationship Between the FRAX Tool and Bone Turnover Markers in Postmenopausal Osteoporosis

, 2013
Aim: In this study, we aimed to show the correlation between the ten-year fracture risk, calculated with FRAX and bone turnover markers (BTM) in a group of postmenopausal women with osteoporosis.
Murat Uludağ, Ülkü Akarırmak, Murat Bolayırlı   +2 more
core   +1 more source

Allelic association in the FRAX region [PDF]

Annals of Human Genetics, 2000
The sex chromosomes enable direct determination of haplotypes, and the analysis of 8 microsatellite markers from the FRAX region on Xq27‐q28 contributes 7219 independent haplotypes from our study in Wessex. Allelic association increases with frequency of alleles, and is less for trinucleotide than dinucleotide repeats.
Ennis, S., Collins, A., Murray, A., MacPherson, J.N., Morton, N.E.   +4 more
openaire   +3 more sources

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Do Additional Clinical Risk Factors Improve the Performance of Fracture Risk Assessment Tool (FRAX) Among Postmenopausal Women? Findings From the Women's Health Initiative Observational Study and Clinical Trials

JBMR Plus, 2019
The ability of the fracture risk assessment tool (FRAX) to discriminate between women who do and do not experience major osteoporotic fractures (MOFs) is suboptimal. Adding common clinical risk factors may improve discrimination.
Carolyn J Crandall, Joseph Larson, Jane A Cauley, John T Schousboe, Andrea Z LaCroix, John A Robbins, Nelson B Watts, Kristine E Ensrud   +7 more
doaj   +1 more source

PGT-M With or Without Triplet Repeat Detection for Fragile X Syndrome

Fertility & Reproduction, 2022
Background: Fragile X syndrome (FraX) is the most common single gene cause of intellectual disability. It is caused by an unstable triplet repeat expansion in the Fragile X Mental Retardation 1 ( FMR1 ) gene.
Katherine ROSE, Tiki OSIANLIS, Martin HEALEY, Sarah NOWOWEISKI, Anand VASUDEVAN   +4 more
doaj   +1 more source

Systematic screening for age‐related comorbidities: Health care optimization among persons with HIV in an outpatient setting

HIV Medicine, EarlyView.
Abstract Background Age‐related comorbidities occur earlier and more frequently in people with HIV (PWH) than in the general population and have emerged as a key challenge in long‐term HIV care. Unfortunately, many of these conditions remain undiagnosed, and systematic screening in clinical practice remains limited.
Anna Katrine Haslund Roed, Anne‐Mette Lebech, Sabine Singh, Ole Kirk, Susanne Dam Nielsen   +4 more
wiley   +1 more source

[Osteoporosis - whom to treat? The importance of FRAX® in Switzerland]

, 2012
The WHO fracture risk assessment tool FRAX® is a computer based algorithm that provides models for the assessment of fracture probability in men and women.
Lippuner, Kurt
core   +1 more source

FRAX® assessment of osteoporotic fracture probability in Switzerland [PDF]

, 2009
A Swiss-specific FRAX model was developed. Patient profiles at increased probability of fracture beyond currently accepted reimbursement thresholds for bone mineral density (BMD) measurement by dual X-ray absorptiometry (DXA), and osteoporosis treatment ...
Johansson, H., Rizzoli, R, Kanis, John A., Johansson, Helena, Johansson, Helena,, Kanis, J. A., Rizzoli, René, Lippuner, K., Lippuner, Kurt, Lippuner, K, Kanis, J A   +10 more
core   +1 more source