Results 51 to 60 of about 5,665 (183)

FRAXE and mental retardation. [PDF]

Journal of Medical Genetics, 1995
Mental impairment and instability of the CCG repeat at FRAXE is described in six kindreds. Cosegregation of FRAXA and FRAXE was found within one of these kindreds. Cytogenetic expression of FRAXE was shown to skip a generation when associated with a reduction in size of the CCG expansion when transmitted through a male; however, in general ...
Mulley, J., Yu, S., Loesch, D., Hay, D., Donnelly, A., Gedeon, A., Carbonell, P., Lopez, I., Glover, G., Garbarron, I., Yu, P., Baker, E., Haan, E., Hockey, A., Knight, S., Daview, K., Richards, R., Sutherland, G.   +17 more
openaire   +4 more sources

Breaking the Debilitating Cycle: Pathophysiology, Assessment, and Multimodal Intervention of Secondary Debilitation After Hip Fracture in Older Adults—A Narrative Review

Orthopaedic Surgery, EarlyView.
This article provides a comprehensive overview of the pathophysiological mechanisms underlying “secondary debilitation after hip fracture,” discusses the clinical application of risk assessment tools, and presents a phased, stepwise intervention strategy aimed at interrupting the “vicious cycle.” ABSTRACT Hip fractures pose a serious threat to the ...
Wenyang Xu, Fan Xu, Maoqiang Fan, Yao Liu, Zhe Song   +4 more
wiley   +1 more source

The Discriminative Ability of FRAX and Possible FRAX-based Intervention Thresholds for Beijing-dwelling People [PDF]

Zhongguo quanke yixue
Background The overall diagnosis and treatment rate of osteoporotic fractures is low in our county, and there is an urgent need to find reliable prediction tools.
LIU Yangxiaoou, SUN Yange, YU Su, DU Xueping, HUANG Kai, YAN Yan, LI Chao
doaj   +1 more source

Psychiatric and Cognitive Features in Italian Women With the FMR1 Premutation: A Comprehensive Assessment Using SCID‐5 and Standardized Cognitive Measures

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 6, Page 406-419, September 2026.
ABSTRACT Women with the FMR1 premutation (PM) are at increased risk for fragile X‐associated conditions (FXPAC), including cognitive and psychiatric features collectively termed fragile X‐associated neuropsychiatric disorders (FXAND). This study is the first to systematically investigate cognitive and psychiatric features in Italian female premutation ...
Federica Alice Maria Montanaro, Randi J. Hagerman, Giuseppina Spano, Flora Tassone, Giancarlo Logroscino, Andrea Bosco   +5 more
wiley   +1 more source

A Systematic Review and Taxonomy of Fall Detection in Geriatric Care: Current State, Challenges, and Applications

WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 3, September 2026.
Overview of fall‐detection approaches and technologies in geriatric care. ABSTRACT This systematic review provides a critical examination of fall detection (FD) technologies in geriatric care, analyzing both technological innovations and implementation challenges across diverse healthcare environments.
Hamid Ali, Ji Zhang, Xiaohui Tao, Raj Gururajan, Xujuan Zhou, Yuquan Gan, Josh Jia‐Ching Ying   +6 more
wiley   +1 more source

Prescribing of Medication to Prevent Glucocorticoid Harms in Patients With Polymyalgia Rheumatica: A Cross‐Sectional Study and Two Emulated Target Trials in the Clinical Practice Research Datalink Aurum

Arthritis &Rheumatology, Volume 78, Issue 8, Page 1731-1740, August 2026.
Objective Polymyalgia rheumatica (PMR) is a common indication for long‐term glucocorticoid (GC) treatment. Bone‐protective and gastroprotective medications are recommended for those at high risk of adverse events from GCs, but no trials have evaluated their effectiveness in PMR.
Helen Twohig, David Jenkinson, James Bailey, Samantha Hider, Ian C. Scott, Sara Muller   +5 more
wiley   +1 more source

A new cut-off value of FRAX tools as an osteoporosis screening tool for Thai geriatric population

Scientific Reports
Identifying osteoporosis in geriatric populations is essential for fragility fracture prevention. While dual-energy X-ray absorptiometry (DXA) remains the gold standard for diagnosing osteoporosis, its availability and cost for mass screening are limited.
Apichat Asavamongkolkul, Nath Adulkasem, Ekasame Vanitcharoenkul, Chandhanarat Chandhanayingyong, Panai Laohaprasitiporn, Krabkaew Soparat, Pojchong Chotiyarnwong, Aasis Unnanuntana   +7 more
doaj   +1 more source

Fracture risk assessment score (FRAX) in postmenopausal women and its relation to hearing loss

Minia Journal of Medical Research
Aim of Study To investigate the relationship between Fracture risk assessment score (FRAX) and hearing loss in females with postmenopausal osteoporosis.
Esraa Abdullah, Abrar Abdelsabour, Rasha Abdel-Magied, Fatma Refaat, Hanaa Sadek   +4 more
doaj   +1 more source

Waist‐to‐Body Mass Index Ratio and Risk of Musculoskeletal Disease in Type 2 Diabetes: A Cohort and PhIP‐Seq Analysis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Musculoskeletal complications in type 2 diabetes (T2DM) are inadequately captured by body mass index (BMI). Waist‐to‐BMI ratio (WBR) may better reflect adverse body composition. We examined cross‐sectional and longitudinal associations between WBR and musculoskeletal disorders in T2DM.
Yongze Zhang, Luxi Lin, Lifeng Zheng, Xiaohuang Lin, Zhaowei Xu, Ximei Shen, Lingning Huang, Fengying Zhao, Sunjie Yan   +8 more
wiley   +1 more source

Progress of osteoporosis: stratification of fracture risk

Остеопороз и остеопатии, 2018
Background: There are two approaches to identify candidates for the prescription of osteoporosis treatment: identification of patients with low bone mineral density using DEXA of the axial skeleton and calculation of the 10-year probability of major ...
Oksana A. Nikitinskaya, Natalya V. Toroptsova   +1 more
doaj   +1 more source