Results 101 to 110 of about 5,660 (167)

Longitudinal analysis shows GAA1 length and baseline clinical status as robust predictors of progression in Friedreich ataxia. [PDF]

J Neurol
Manrique L, Martínez-Dubarbie F, Pelayo-Negro AL, Benitez-Calle N, Sanchez-Pelaez MV, Cota-Gonzalez D, Loza R, Martinez-Díaz R, Irure-Ventura J, Sanchez-Quintana C, Sanchez I, Matilla-Dueñas A, Infante J.   +12 more
europepmc   +1 more source

Impaired Glur2 palmitoylation in cerebellar Purkinje cells of a Friedreich ataxia mouse model. [PDF]

Exp Neurol
Mercado-Ayón E, Coulman J, Lee JY, Lancaster E, Goga E, Asad M, Witze E, Lynch DR.   +7 more
europepmc   +1 more source

Safety and preliminary efficacy of autologous bone marrow-derived mesenchymal stem cell transplantation in hereditary cerebellar ataxia: phase I/IIa clinical trial. [PDF]

Stem Cell Res Ther
Moghaddam AS, Tavakol-Afshari J, Farkhad NK, Mojarrad M, Eslami M, Savad S, Khodadoust MA, Orafaie A, Sobhani M, Farmanbar A, Dashtkoohi M, Khodayari H, Hassani D, Najafi S, Najafi P, Hescheler J, Nayernia K, Boroumand A.   +17 more
europepmc   +1 more source

Impact of Omaveloxolone on Serum Lipids in Patients with Friedreich Ataxia: A 1-Year Real-World Analysis. [PDF]

CNS Drugs
Buchinger D, Scherer T, Dalos D, Milenkovic I.   +3 more
europepmc   +1 more source

Evolution of Friedreich's Ataxia Management Across Established and Emerging Therapies-Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Garah B, Aljabri H, Aljohani A, Alnuzha E, Maihoub A, Almuzaini R, Aljohani L, Alshamani L, Alluqmani M.   +8 more
europepmc   +1 more source

Slowing the curve: a single-arm meta-analysis of mFARS outcomes following omaveloxolone treatment in Friedreich ataxia. [PDF]

BMJ Neurol Open
Ali A, Cheema WA, Nisar F, Reyaz U, Saad M, Talha M, Sarfraz S, Butt A, Shamoon M, Abdullah A, Shabbir MA, Talha M, Azam H, Abdullah M, Anwaar A.   +14 more
europepmc   +1 more source

The TRKB Agonist 7,8-dihydroxyflavone Alleviates DNA Damage and Apoptosis in a Neuronal Cell Model of Friedreich's Ataxia. [PDF]

Mol Neurobiol
Galán-Cruz J, Vicente-Acosta A, Loría F, Díaz-Nido J, Herranz-Martín S.   +4 more
europepmc   +1 more source

Advanced Heart Failure in Friedreich's Ataxia: A Story of Challenges, Opportunities, and Hope. [PDF]

JACC Case Rep
Miyashita S, Zaki A, Schlabach K, Kim G, Vierecke JK, Lynch D, Tan C, Hsich E, Alvarez P.   +8 more
europepmc   +1 more source

Transcription and cohesin direct domain boundary spatial positioning and are linked to Friedreich's ataxia. [PDF]

Mol Cell
Karnay A, Linares-Saldana R, Wang Q, Gardner Z, Liang JA, Santini GT, Haridhasapavalan KK, Nguyen SC, Hugelier S, Shewale B, Kanemaki MT, Napierala JS, Napierala M, Wilson RB, Dubois N, Poleshko A, Kim W, Shah PP, Lakadamyali M, Joyce EF, Jain R.   +20 more
europepmc   +1 more source

Mitochondrial iron overload is associated with lysosomal dysfunction-mediated mitophagy impairment in the heart of Friedreich's ataxia. [PDF]

Mitochondrion
Jee E, Medha M, Baek H, Kim J, Kim Y.
europepmc   +1 more source