Iron-Induced Oxidative Stress in Human Diseases
Cells, 2022 Iron is responsible for the regulation of several cell functions. However, iron ions are catalytic and dangerous for cells, so the cells sequester such redox-active irons in the transport and storage proteins.
Teruyuki Kawabata
doaj +1 more source
Quantifying Integrated Proteomic Responses to Iron Stress in the Globally Important Marine Diazotroph Trichodesmium. [PDF]
PLoS ONE, 2015 Trichodesmium is a biogeochemically important marine cyanobacterium, responsible for a significant proportion of the annual 'new' nitrogen introduced into the global ocean.
Joseph T Snow +7 more
doaj +1 more source
Transferrin and Lactoferrin – Human Iron Sources for Enterococci [PDF]
Polish Journal of Microbiology, 2017 To overcome limitations in iron acquisition, enterococci have evolved a number of mechanisms to scavenge iron from the host iron-binding proteins – transferrin (TR) and lactoferrin (LF).
Paweł Lisiecki
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Iron-sulfur proteins play essential roles in a wide variety of cellular processes such as respiration, photosynthesis, nitrogen fixation and magnetoreception.
Tianyang Tong +25 more
doaj +1 more source
The Relationship between Environmental Dioxygen and Iron-Sulfur Proteins Explored at the Genome Level. [PDF]
PLoS ONE, 2017 About 2 billion years ago, the atmosphere of the Earth experienced a great change due to the buildup of dioxygen produced by photosynthetic organisms.
Claudia Andreini +2 more
doaj +1 more source
Anaerobic Expression and Purification of Holo-CCIS, an Artificial Iron-sulfur Protein
Bio-Protocol, 2021 Iron-sulfur proteins are ubiquitous among all living organisms and are indispensable for almost all metabolic pathways ranging from photosynthesis, respiration, nitrogen, and carbon dioxide cycles.
Bhanu Jagilinki +3 more
doaj +1 more source
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Communications Biology, 2021 Bell et al. report 46 new loci associated with biomarkers of iron homeostasis, including ferritin levels, iron binding capacity, and iron saturation, in the Icelandic, Danish and UK populations.
Steven Bell +61 more
doaj +1 more source
Escherichia coli RIC is able to donate iron to iron-sulfur clusters. [PDF]
PLoS ONE, 2014 Escherichia coli RIC (Repair of Iron Centers) is a diiron protein previously reported to be involved in the repair of iron-sulfur proteins damaged by oxidative or nitrosative stresses, and proposed to act as an iron donor.
Lígia S Nobre +6 more
doaj +1 more source
Iron binding at specific sites within the octameric HbpS protects streptomycetes from iron-mediated oxidative stress. [PDF]
PLoS ONE, 2013 The soil bacterium Streptomyces reticuli secretes the octameric protein HbpS that acts as a sensory component of the redox-signalling pathway HbpS-SenS-SenR. This system modulates a genetic response on iron- and haem-mediated oxidative stress.
Ina Wedderhoff +3 more
doaj +1 more source
The Fate of Iron in The Organism and Its Regulatory Pathways
Acta Medica, 2005 Iron is an essential element involved in many life-necessary processes. Interestingly, in mammals there is no active excretion mechanism for iron. Therefore iron kinetics has to be meticulously regulated.
Přemysl Mladěnka +3 more
doaj +1 more source