Results 11 to 20 of about 204,163 (265)
Iron binding at specific sites within the octameric HbpS protects streptomycetes from iron-mediated oxidative stress. [PDF]
The soil bacterium Streptomyces reticuli secretes the octameric protein HbpS that acts as a sensory component of the redox-signalling pathway HbpS-SenS-SenR. This system modulates a genetic response on iron- and haem-mediated oxidative stress.
Ina Wedderhoff +3 more
doaj +1 more source
Iron-tracking strategies: Chaperones capture iron in the cytosolic labile iron pool
Cells express hundreds of iron-dependent enzymes that rely on the iron cofactors heme, iron-sulfur clusters, and mono-or di-nuclear iron centers for activity.
Caroline C. Philpott +6 more
doaj +1 more source
Nutrient adaptation is key in limiting environments for the promotion of microbial growth and survival. In microbial systems, iron is an essential component for many cellular processes, and bioavailability varies greatly among different conditions.
Benjamin Muselius +3 more
doaj +1 more source
Monomeric Yeast Frataxin Is an Iron-Binding Protein [PDF]
Friedreich's ataxia, an autosomal cardio- and neurodegenerative disorder that affects 1 in 50,000 humans, is caused by decreased levels of the protein frataxin. Although frataxin is nuclear-encoded, it is targeted to the mitochondrial matrix and necessary for proper regulation of cellular iron homeostasis.
Jeremy D, Cook +8 more
openaire +2 more sources
Iron-sulfur clusters are prosthetic groups of proteins involved in various biological processes. However, details of the immature state of the iron-sulfur cluster into proteins have not yet been elucidated. We report here the first structural analysis of
Erika Tsutsumi +9 more
doaj +1 more source
Lactoferrin‐an iron binding protein in synovial fluid [PDF]
AbstractThis study was initiated in an attempt to confirm recent reports that mycoplasmas can be regularly isolated from human rheumatoid tissue, and that joint lesions can be induced in mice and chicks by injection of human rheumatoid synovium. All synovial tissues were free of mycoplasmas including T‐strains.
R M, Bennett +2 more
openaire +2 more sources
Iron-Utilization System in Vibrio vulnificus M2799
Vibrio vulnificus is a Gram-negative pathogenic bacterium that causes serious infections in humans and requires iron for growth. A clinical isolate, V. vulnificus M2799, secretes a catecholate siderophore, vulnibactin, that captures ferric ions from the ...
Katsushiro Miyamoto +10 more
doaj +1 more source
Phase variation in Myxococcus xanthus yields cells specialized for iron sequestration. [PDF]
Myxococcus xanthus undergoes phase variation during growth to produce predominantly two colony phenotypes. The majority are yellow colonies containing swarm-proficient cells and a minority are tan colonies containing swarm-deficient cells.
Katarzyna Dziewanowska +5 more
doaj +1 more source
Trichomonas vaginalis is one of the most common sexually transmitted parasites in humans. This protozoan has high iron requirements for growth, metabolism, and virulence. However, iron concentrations also differentially modulate T.
Claudia R. León-Sicairos +3 more
doaj +1 more source
Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1.
BackgroundMembers of the WhiB-like (Wbl) protein family possess iron-sulfur clusters and are implicated in the regulation of developmental processes in Actinomycetes. Mycobacterium tuberculosis possesses seven Wbl proteins.
Laura J Smith +3 more
doaj +1 more source

