Results 11 to 20 of about 204,163 (265)

Iron binding at specific sites within the octameric HbpS protects streptomycetes from iron-mediated oxidative stress. [PDF]

open access: yesPLoS ONE, 2013
The soil bacterium Streptomyces reticuli secretes the octameric protein HbpS that acts as a sensory component of the redox-signalling pathway HbpS-SenS-SenR. This system modulates a genetic response on iron- and haem-mediated oxidative stress.
Ina Wedderhoff   +3 more
doaj   +1 more source

Iron-tracking strategies: Chaperones capture iron in the cytosolic labile iron pool

open access: yesFrontiers in Molecular Biosciences, 2023
Cells express hundreds of iron-dependent enzymes that rely on the iron cofactors heme, iron-sulfur clusters, and mono-or di-nuclear iron centers for activity.
Caroline C. Philpott   +6 more
doaj   +1 more source

Iron Limitation in Klebsiella pneumoniae Defines New Roles for Lon Protease in Homeostasis and Degradation by Quantitative Proteomics

open access: yesFrontiers in Microbiology, 2020
Nutrient adaptation is key in limiting environments for the promotion of microbial growth and survival. In microbial systems, iron is an essential component for many cellular processes, and bioavailability varies greatly among different conditions.
Benjamin Muselius   +3 more
doaj   +1 more source

Monomeric Yeast Frataxin Is an Iron-Binding Protein [PDF]

open access: yesBiochemistry, 2006
Friedreich's ataxia, an autosomal cardio- and neurodegenerative disorder that affects 1 in 50,000 humans, is caused by decreased levels of the protein frataxin. Although frataxin is nuclear-encoded, it is targeted to the mitochondrial matrix and necessary for proper regulation of cellular iron homeostasis.
Jeremy D, Cook   +8 more
openaire   +2 more sources

Structure of a putative immature form of a Rieske-type iron-sulfur protein in complex with zinc chloride

open access: yesCommunications Chemistry, 2023
Iron-sulfur clusters are prosthetic groups of proteins involved in various biological processes. However, details of the immature state of the iron-sulfur cluster into proteins have not yet been elucidated. We report here the first structural analysis of
Erika Tsutsumi   +9 more
doaj   +1 more source

Lactoferrin‐an iron binding protein in synovial fluid [PDF]

open access: yesArthritis & Rheumatism, 1973
AbstractThis study was initiated in an attempt to confirm recent reports that mycoplasmas can be regularly isolated from human rheumatoid tissue, and that joint lesions can be induced in mice and chicks by injection of human rheumatoid synovium. All synovial tissues were free of mycoplasmas including T‐strains.
R M, Bennett   +2 more
openaire   +2 more sources

Iron-Utilization System in Vibrio vulnificus M2799

open access: yesMarine Drugs, 2021
Vibrio vulnificus is a Gram-negative pathogenic bacterium that causes serious infections in humans and requires iron for growth. A clinical isolate, V. vulnificus M2799, secretes a catecholate siderophore, vulnibactin, that captures ferric ions from the ...
Katsushiro Miyamoto   +10 more
doaj   +1 more source

Phase variation in Myxococcus xanthus yields cells specialized for iron sequestration. [PDF]

open access: yesPLoS ONE, 2014
Myxococcus xanthus undergoes phase variation during growth to produce predominantly two colony phenotypes. The majority are yellow colonies containing swarm-proficient cells and a minority are tan colonies containing swarm-deficient cells.
Katarzyna Dziewanowska   +5 more
doaj   +1 more source

The Non-Canonical Iron-Responsive Element of IRE-tvcp12 Hairpin Structure at the 3′-UTR of Trichomonas vaginalis TvCP12 mRNA That Binds TvHSP70 and TvACTN-3 Can Regulate mRNA Stability and Amount of Protein

open access: yesPathogens, 2023
Trichomonas vaginalis is one of the most common sexually transmitted parasites in humans. This protozoan has high iron requirements for growth, metabolism, and virulence. However, iron concentrations also differentially modulate T.
Claudia R. León-Sicairos   +3 more
doaj   +1 more source

Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1.

open access: yesPLoS ONE, 2012
BackgroundMembers of the WhiB-like (Wbl) protein family possess iron-sulfur clusters and are implicated in the regulation of developmental processes in Actinomycetes. Mycobacterium tuberculosis possesses seven Wbl proteins.
Laura J Smith   +3 more
doaj   +1 more source

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