Results 101 to 110 of about 190,999 (265)

SARS-CoV-2 Mpro responds to oxidation by forming disulfide and NOS/SONOS bonds

Nature Communications
The main protease (Mpro) of SARS-CoV-2 is critical for viral function and a key drug target. Mpro is only active when reduced; turnover ceases upon oxidation but is restored by re-reduction.
Patrick Y. A. Reinke, Robin Schubert, Dominik Oberthür, Marina Galchenkova, Aida Rahmani Mashhour, Sebastian Günther, Anaïs Chretien, Adam Round, Brandon Charles Seychell, Brenna Norton-Baker, Chan Kim, Christina Schmidt, Faisal H. M. Koua, Alexandra Tolstikova, Wiebke Ewert, Gisel Esperanza Peña Murillo, Grant Mills, Henry Kirkwood, Hévila Brognaro, Huijong Han, Jayanath Koliyadu, Joachim Schulz, Johan Bielecki, Julia Lieske, Julia Maracke, Juraj Knoska, Kristina Lorenzen, Lea Brings, Marcin Sikorski, Marco Kloos, Mohammad Vakili, Patrik Vagovic, Philipp Middendorf, Raphael de Wijn, Richard Bean, Romain Letrun, Seonghyun Han, Sven Falke, Tian Geng, Tokushi Sato, Vasundara Srinivasan, Yoonhee Kim, Oleksandr M. Yefanov, Luca Gelisio, Tobias Beck, Andrew S. Doré, Adrian P. Mancuso, Christian Betzel, Saša Bajt, Lars Redecke, Henry N. Chapman, Alke Meents, Dušan Turk, Winfried Hinrichs, Thomas J. Lane   +54 more
doaj   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Correlated Metal LaNiO3 as a p‐Type Transparent Conductor

Advanced Functional Materials, EarlyView.
p‐type transparent conducting oxides are needed to enable superstrate solar cell geometries with n‐type absorbers. The p‐type correlated metal LaNiO3 combines high optical transmission with low electrical resistivity and is compatible with a range of scalable deposition processes.
Shivang Beniwal, Emmeline G. Poole, Jacob Plowman, Troy D. Manning, Teresa Partida Manzanera, Kevin Sanderson, Matthew S. Dyer, Matthew J. Rosseinsky, Jonathan Alaria   +8 more
wiley   +1 more source

A Novel Modified Petroresin Particle (MPRP) With Enhanced Oil–Water Selectivity for Cold Production in Heavy Oil Reservoirs

Advanced Functional Materials, EarlyView.
A novel oil–water selective conformance control agent, MPRP, is prepared via hydrophilic grafting and mechanical granulation. MPRP uniformly disperses in water, cohesively expands upon aging, and readily dissolves in the oil phase. During conformance control, it selectively aggregates in water channeling pathways to form effective plugs without ...
Guang Zhao, Dongfang Lv, Chang Liu, Changxu Wu, Yifei Liu, Caili Dai, Huazhou Li   +6 more
wiley   +1 more source

Convergent-beam attosecond x-ray crystallography

Structural Dynamics
Sub-ångström spatial resolution of electron density coupled with sub-femtosecond to few-femtosecond temporal resolution is required to directly observe the dynamics of the electronic structure of a molecule after photoinitiation or some other ultrafast ...
Henry N. Chapman, Chufeng Li, Saša Bajt, Mansi Butola, J. Lukas Dresselhaus, Dmitry Egorov, Holger Fleckenstein, Nikolay Ivanov, Antonia Kiene, Bjarne Klopprogge, Viviane Kremling, Philipp Middendorf, Dominik Oberthuer, Mauro Prasciolu, T. Emilie S. Scheer, Janina Sprenger, Jia Chyi Wong, Oleksandr Yefanov, Margarita Zakharova, Wenhui Zhang   +19 more
doaj   +1 more source

Dissociation process of polyalanine aggregates by free electron laser irradiation. [PDF]

PLoS One, 2023
Okumura H, Itoh SG, Zen H, Nakamura K.
europepmc   +1 more source

Ambient‐Stable Transparent P‐Type CuI Transistors Via Room‐Temperature Pulsed Laser Deposition

Advanced Functional Materials, EarlyView.
An in situ PLD fabricated AlOx${\rm AlO}_x$/CuI/AlOx${\rm AlO}_x$ sandwich structure enables stable CuI TFTs with a field‐effect mobility of 2.3 ±$\pm$ 0.7 cm2${\rm cm}^{2}$ V−1${\rm V}^{-1}$ s−1${\rm s}^{-1}$ and excellent ambient stability. Complementary inverters based on CuI:Rb and ZnO:Al exhibit rail‐to‐rail voltage transfer characteristics and an
Yang Chen, Susanne Selle, Michael S. Bar, Michael Lorenz, Holger von Wenckstern, Marius Grundmann   +5 more
wiley   +1 more source

Polarization‐Dependent Synaptic‐Like Electro‐Optical Response in Ferroelectric Nematic Liquid Crystals

Advanced Functional Materials, EarlyView.
Ferroelectric nematic liquid crystals (FNLCs) offer fast, tunable polarization and low‐voltage operation but suffer from poor polarization retention at zero field. Semiconductor‐modified FNLCs enhance polarization retention and exhibit short‐ and long‐term electro‐optical responses, while also supporting spike‐type signal integrations.
Kutay Sagdic, Weiming Yao, Danqing Liu
wiley   +1 more source

Halide Perovskite Integrated Photovoltaic Cathodes Incorporating Pt on ZIF‐8‐Derived Carbon for Solar Hydrogen Production

Advanced Functional Materials, EarlyView.
A low‐Pt catalyst supported on zeolitic imidazolate framework (ZIF‐8)‐derived porous carbon and graphite is integrated with a halide perovskite photovoltaic, yielding cathodes that achieve a high photocurrent density (∼20 mA cm−2) under simulated sunlight and exhibit remarkable stability in acidic media over several days, thereby demonstrating a ...
Na Yeong Oh, Woo Jin Mun, Kamran Dastafkan, Matyas Daboczi, Hongki Kim, Humza Bhatti, Eunyoung Hong, Minzhi Chen, Yongqi Huang, Jin Hyuk Kim, Nicola Gasparini, Jong Hak Kim, Salvador Eslava   +12 more
wiley   +1 more source

Charge Generation and Recombination Pathways in All‐Polymer Bulk Heterojunction Solar Cells

Advanced Functional Materials, EarlyView.
Multimodal spectroscopy and device analysis reveal how field‐dependent charge generation, transport limitations, and non‐geminate recombination govern performance losses in all polymer solar cells. The results identify the key processes controlling charge extraction and recombination, providing insights for the design of more efficient all‐polymer ...
Shahidul Alam, Wejdan Althobaiti, Safakath Karuthedath, Christopher E. Petoukhoff, Amr Dahman, Khawla Alkhezaim, Oleksandr Matiash, José P. Jurado, Mariia Ferree, Ning Su, Jacob Blaskovits, Denis Andrienko, Vladimir Dyakonov, Andreas Sperlich, Vojtech Nádaždy, Tobin J. Marks, Antonio Facchetti, Frédéric Laquai   +17 more
wiley   +1 more source