Results 71 to 80 of about 6,942,124 (246)

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Optimisation of a tubular linear machine with permanent magnets for wave energy extraction

, 2011
PurposeThe purpose of this paper is to optimise the cost-based performance of a tubular linear generator and to minimise cogging forces.Design/methodology/approachOptimisation of a tubular linear generator with longitudinal flux topology has been ...
Rotaru, Mihai D., Thomas S. Parel, Mihai D. Rotaru, Parel, Thomas S., Sykulski, Jan K., Grant E. Hearn, Jan K. Sykulski, Hearn, Grant E.   +7 more
core   +1 more source

ICEIT 2024 - 59 Linear Generators: Comparison between Five – Phase and Three – Phase machines

Zanco Journal of Pure and Applied Sciences
Linear electrical power generation is one of the methods to generate electrical power from linear moving forces with zero unwanted CO and NO emissions.
Aslan Sa. Jalal
doaj   +1 more source

Effect of Injection Timing on the Operation of Hydrogen-Fuelled Free-Piston Linear Generator Engine during Starting

International Journal of Automotive Engineering, 2013
A linear engine type with piston assembly that swings between two oppositely placed combustion chambers considered in this study. The study investigated the effect of injection timing on starting of the engine.
Ibrahim Abdulwehab A., Abidin Ezrann Zharif B. Zainal, Aziz Rashid A., Zulkifli Saiful A.   +3 more
doaj   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management

Advanced Science, EarlyView.
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao, Guifang Pan, Jincai Zhang, Yue Gong, Wenjian Zhang, Huiling Shen, Xingxing Li, Yuehan Ouyang, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

DESIGN AND ANALYSIS OF FREE PISTON LINEAR GENERATOR ENGINE [PDF]

, 2022
Gelişen otomotiv teknolojilerinde elektrikli araçlar ileri derece öneme sahip olmaktadır. Bunun sonucu olarak elektrik enerjisi ile çalışan motorlar, elektrik depolama teknolojileri, fosil yakıtları elektrik enerjisine çeviren sistemler (jeneratörler ...
Daşkın, Burak
core   +1 more source

Electromagnetic Characteristics Analysis of a Tubular Moving Magnet Linear Generator System

Applied Sciences, 2020
As a new type of advanced electrical power generation system, free-piston engines can be applied to many fields, such as electric vehicles and communication base stations.
Yunqin Hu, Zhaoping Xu, Ye Sun, Liang Liu   +3 more
doaj   +1 more source

Lactate‐H3K18la‐RPL11 Axis Drives Gemcitabine Resistance in Pancreatic Cancer by Integrating Protein Synthesis and DNA Damage Repair

Advanced Science, EarlyView.
A lactate‐H3K18la epigenetic axis upregulates RPL11 to drive gemcitabine resistance in pancreatic cancer. RPL11 orchestrates chemoresistance through a dual, compartmentalized role: enhancing cytoplasmic protein synthesis via EEF1A1 stabilization and promoting nuclear DNA damage repair by co‐activating PARP14, thus ensuring robust cell survival ...
Lijun Zhao, Jianzhong Cao, Wenyue Liu, Xuyun Li, Haolin Zhang, Xiaofang Zhang, Shiyang Shi, Huilong Yin, Junjie Li, Angang Yang, Rui Zhang   +10 more
wiley   +1 more source

Microstructure Evolution in Dry‑Coated Sulfidic All‐Solid‐State Battery Cathodes: Investigating Core–Shell Particle Morphology

Advanced Science, EarlyView.
Mixing method directly governs interface engineering and electrode morphology during the dry coating of all‐solid‐state battery cathodes. While high‐shear batch mixing yields poor electrode quality and lacks core–shell‐like features, continuous extruder mixing enables strong binder fibrillation and a core–shell‐like coating between the active material ...
Michael Wolf, Aaron Stoeckle, Rebecca Wilhelm, Maximilian A. Plass, Milad Hosseini, Johannes Kriegler, Korbinian Huber, Simon Lux   +7 more
wiley   +1 more source