Results 61 to 70 of about 7,275,136 (257)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Modulated Quasi-Continuous-Wave Laser Module for Free-Space Optics

Photonics
A quasi-continuous-wave (QCW) laser module based on a half-bridge structure is proposed for the low-voltage silicon photonics application, which forms a continuous-wave (CW) laser output when it equally distributes the heat dissipation into all lasers ...
Chun-Hao Chen, Chun-Hsiung Lin, Hao-Chung Kuo, Yu-Heng Hong, Ching-Yao Liu, Kai-En Lin, Yueh-Tsung Shieh, Shyr-Long Jeng, Edward-Yi Chang, Wei-Hua Chieng   +9 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Α dual‐hop equivalent structure of a generalised multi‐hop free‐space optics network

IET Communications, 2021
The performance of free‐space optics links strongly depends on scintillation effects caused by the atmospheric turbulence appearance. A widely adopted way to counterbalance the expected deterioration due to scintillation is to employ cooperative and ...
Nikolaos A. Androutsos, Hector E. Nistazakis, Harilaos G. Sandalidis, Erich Leitgeb, George S. Tombras   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A high bit rate free space optics based ring topology having carrier‐less nodes

IET Communications, 2021
A free space optics based ring topology that transmits full‐duplex data to four different nodes in the ring is proposed. The link is designed such that the four nodes do not require a local optical source to transmit the uplink data.
Jawad Mirza, Waqas A. Imtiaz, Abdulah Jeza Aljohani, Salman Ghafoor   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Experimental investigation of the performance of different modulation techniques under controlled FSO turbulence channel [PDF]

, 2010
This paper experimentally investigates and compares the performance of the free space optics system employing three different modulation schemes, on-off keying (OOK) with nonreturn- to-zero (NRZ) and return-to-zero (RZ) and the binary phase shift keying (
Z. Ghassemlooy, Adebanjo, Olusegun, O. Adebanjo, S. Ansari, S. Rajbhandari, Ghassemlooy, Zabih, H. Le Minh, Ansari, S., A. Gholami, Rajbhandari, Sujan, Ijaz, Muhammad, M. Ijaz, Le Minh, Hoa   +12 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The propagation of Hermite–Gauss wave packets in optics and quantum mechanics

Natural Sciences
The two‐dimensional paraxial equation of optics and the two‐dimensional time‐dependent Schrödinger equation, derived as approximations of the three‐dimensional Helmholtz equation and the three‐dimensional time‐independent Schrödinger equation ...
John S. Briggs
doaj   +1 more source