Results 61 to 70 of about 7,598,998 (257)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Investigations of Quantum Cascade Lasers for Free Space Optics Operating at the Wavelength Range of 8-12 μm [PDF]

, 2011
The paper presents analysis and preliminary investigations of quantum cascade lasers for free space optics. The lasers radiate in the long wavelength IR spectral range (8-12 μm). Because of lower effects of radiation scattering than in the case of 1.5 μm
Szabra, D., Nowakowski, M., Bielecki, Z., Gutowska, M., Wojtas, J., Mikołajczyk, J.   +5 more
core   +1 more source

Million-Q free space meta-optical resonator at near-visible wavelengths

Nature Communications
High-quality (Q)-factor optical resonators with extreme temporal coherence are of both technological and fundamental importance in optical metrology, continuous-wave lasing, and semiconductor quantum optics.
Jie Fang, Rui Chen, David Sharp, Enrico M. Renzi, Arnab Manna, Abhinav Kala, Sander A. Mann, Kan Yao, Christopher Munley, Hannah Rarick, Andrew Tang, Sinabu Pumulo, Yuebing Zheng, Vinod M. Menon, Andrea Alù, Arka Majumdar   +15 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modulated Quasi-Continuous-Wave Laser Module for Free-Space Optics

Photonics
A quasi-continuous-wave (QCW) laser module based on a half-bridge structure is proposed for the low-voltage silicon photonics application, which forms a continuous-wave (CW) laser output when it equally distributes the heat dissipation into all lasers ...
Chun-Hao Chen, Chun-Hsiung Lin, Hao-Chung Kuo, Yu-Heng Hong, Ching-Yao Liu, Kai-En Lin, Yueh-Tsung Shieh, Shyr-Long Jeng, Edward-Yi Chang, Wei-Hua Chieng   +9 more
doaj   +1 more source

Limits and security of free-space quantum communications

Physical Review Research, 2021
The study of free-space quantum communications requires tools from quantum information theory, optics, and turbulence theory. Here we combine these tools to bound the ultimate rates for key and entanglement distribution through a free-space link, where ...
Stefano Pirandola
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Α dual‐hop equivalent structure of a generalised multi‐hop free‐space optics network

IET Communications, 2021
The performance of free‐space optics links strongly depends on scintillation effects caused by the atmospheric turbulence appearance. A widely adopted way to counterbalance the expected deterioration due to scintillation is to employ cooperative and ...
Nikolaos A. Androutsos, Hector E. Nistazakis, Harilaos G. Sandalidis, Erich Leitgeb, George S. Tombras   +4 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

A high bit rate free space optics based ring topology having carrier‐less nodes

IET Communications, 2021
A free space optics based ring topology that transmits full‐duplex data to four different nodes in the ring is proposed. The link is designed such that the four nodes do not require a local optical source to transmit the uplink data.
Jawad Mirza, Waqas A. Imtiaz, Abdulah Jeza Aljohani, Salman Ghafoor   +3 more
doaj   +1 more source