Results 1 to 10 of about 1,034 (173)

Comparison of the Behavior for Free Standing Pile Group and Piles of Piled Raft [PDF]

Engineering and Technology Journal, 2018
The intended task of this paper is studying the behavior of free standing pile groups and piles of piled raft driven in clayey soil under axial loading. The raft-piles interaction is investigated as well through the two series of tests. Each one of these
Awf Al-Kaisi, Falah Rahil, Mohanned Waheed   +2 more
doaj   +4 more sources

Physical modeling of behaviors of cast-in-place concrete piled raft compared to free-standing pile group in sand

Journal of Rock Mechanics and Geotechnical Engineering, 2018
Abstract Similar to free-standing pile groups, piled raft foundations are conventionally designed in which the piles carry the total load of structure and the raft bearing capacity is not taken into account. Numerous studies indicated that this method is too conservative.
Mehdi Sharafkhah, Issa Shooshpasha
exaly   +2 more sources

Effect of Cavity in Sandy Soil on Load Distribution of Pile Group [PDF]

Engineering and Technology Journal, 2014
The present study investigates the influence of presence of cavities on adjacent buildings especially in the case of piled structures. The presence of cavity affects on the bearing capacity and settlement of piled foundation.
Mohammed Y. Fattah, Karim H. Ibrahim. Al-Helo, Hala H. Abed   +2 more
doaj   +1 more source

Model tests on free-standing passive pile groups in sand

, 2010
A number of tests have been conducted to investigate response of vertically loaded capped pile groups in sand undergoing uniform lateral soil movement. The development of shear force, bending moment and deflection along the piles was measured. Presented in this paper are 4 tests on 2-pile free-standing groups, with a view to establish solutions for ...
W Guo, E Ghee
openaire   +3 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source