Results 121 to 130 of about 19,018,457 (307)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Correction: Fast and scalable solvent-free access to Lappert's heavier tetrylenes E{N(SiMe<sub>3</sub>)<sub>2</sub>}<sub>2</sub> (E = Ge, Sn, Pb) and ECl{N(SiMe<sub>3</sub>)<sub>2</sub>} (E = Ge, Sn). [PDF]
Chem Sci, 2023 Cabeza JA +4 more
europepmc +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
ComputersTo address the limitations of existing knowledge graph-based recommendation algorithms, including insufficient utilization of semantic information and inadequate modeling of user behavior motivations, we propose SKGRec, a novel recommendation model that ...
Siqi Xu, Ziqian Yang, Jing Xu, Ping Feng
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Dakota Access Pipeline Project, Dakota Access, LLC, Section 408 review area, Mississippi River
vhill 1/12/2016 Mssipp Lat 40.4' Long -SI 3 I I .lllli I t r|| NORTH Proposed Pipetine tsn. uaKota Ac«», LLij; [i.altalflk,Us. •’T^Eanhslir^SB^ DAKOTA Access, uc Dakota Access Pipeline Project Dakota Access, LLC Section 408 Review Area Mississippi River ...
Dakota Access, LLC;
core +2 more sources
The graphite-catalyzed ipso-functionalization of arylboronic acids in an aqueous medium: metal-free access to phenols, anilines, nitroarenes, and haloarenes. [PDF]
RSC Adv, 2021 Dandia A +5 more
europepmc +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Monograph in 'BID' on data webs and knowledge graphs
BiD: Textos Universitaris de Biblioteconomia i Documentació, 2023 Miquel Centelles Velilla
doaj +1 more source