Results 1 to 10 of about 11,994,000 (257)

xperimental Evaluation of the Possibility of using the LAL test to Determine Bacterial Endotoxins in Vaccines for Rabies Prophylaxis

open access: yesЭпидемиология и вакцинопрофилактика, 2021
Relevance. The presence of pyrogenic impurities in finished dosage forms of concentrated cultural anti-rabies vaccines produced in the Russian Federation is determined using pyrogenicity tests on rabbits (in vivo).
A. V. Muhacheva   +7 more
doaj   +1 more source

Evaluation of the Efficacy and Safety of Initial Empirical Antibiotic Therapy for Community-Acquired Pneumonia in Middle-Aged People

open access: yesБезопасность и риск фармакотерапии, 2022
β-lactam antibiotics, including cephalosporins, are the drugs of choice for empirical antibiotic therapy (ABT) in patients with community-acquired pneumonia.
T. V. Alexandrova   +9 more
doaj   +1 more source

Comparative Dissolution Kinetics of Several Multisource Thioctic Acid Products

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2022
The relationship between dissolution and bioavailability is an example of the interdependency between the quality of a medicinal product and its safety and efficacy.
G. F. Vasilenko   +6 more
doaj   +1 more source

Development of a Comprehensive HPLC Method for Determination of Product-related Impurities and Assay of Active Ingredients in Papaverine Hydrochloride Products

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2021
. Papaverine hydrochloride products are used as anticonvulsants in routine medical practice. Most of the approved product specification files include thin-layer chromatography for assessment of product-related impurities and UV spectrophotometry for ...
N. P. Antonova   +6 more
doaj   +1 more source

Determination of Arbutin in Herbal Medicinal Products

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2021
Arbutin is the main active ingredient in many herbal medicinal products that have diuretic, antimicrobial, bactericidal, and antioxidant effects. Many of these products are mixtures of different herbal substances.
N. P. Antonova   +6 more
doaj   +1 more source

Modern methods for identification and quantification of cardiac glycosides

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2023
Scientific relevance. Cardiac glycosides have been used in medicine for over two centuries. Current studies suggest that biologically active substances from this group can be used to treat not only heart conditions but also viral infections, cancers, and
O. V. Evdokimova   +6 more
doaj   +1 more source

POST-MARKETING DRUG SAFETY RESEARCH: ANALYSIS OF RECOMMENDATIONS OF FOREIGN REGULATORS

open access: yesБезопасность и риск фармакотерапии, 2018
The monitoring of information on the safety of various drugs is becoming more relevant day by day, as the number of drugs on the  pharmaceutical market increases, generic drugs, bio-analogous drugs appear.
E. V. Shubnikova   +8 more
doaj   +1 more source

The Adverse Drug Reactions Registered During the Postmarketing Period

open access: yesБезопасность и риск фармакотерапии, 2019
Efficacy, safety and biotransformation features of any drug are fully revealed during widely using. Therefore, postmarketing studies of the pharmacological properties of drugs are an integral component of pharmacovigilance.
E. V. Shubnikova   +8 more
doaj   +1 more source

UNEXPECTED ADVERSE REACTIONS OF THE DRUGS OF THE GROUP OF INHIBITORS OF DIPEPTIDYL PEPTIDASE-4

open access: yesБезопасность и риск фармакотерапии, 2018
Diabetes mellitus is the most acute medical and social problem related to the priorities of national health systems. The dramatic and urgent problems of diabetes mellitus are determined by the high prevalence of diabetes, high mortality and early ...
T. V. Romanova   +10 more
doaj   +1 more source

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