Results 161 to 170 of about 9,093,113 (302)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Propellane-free access to bicyclo[1.1.1]pentanes. [PDF]

Nat Commun
Liu C, Li W, Li R, Merchant RR, Kanda Y, Qin T.   +5 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Periódicos utilizados para publicação pelos pesquisadores de ciência da informação do Brasil e visibilidade nas bases de dados WoS e Scopus

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2014
Pinheiro, Liliana Vierira, Da Silva, Edna Lúcia, Rodríguez, Rosangela Schwarz   +2 more
doaj   +1 more source

The predictors of treatment adherence among hypertensive patients with cost-free access. [PDF]

Sci Rep
Nyande FK, Konlan KD, Asiamah LS, Boateng V, Gbeamir J, Dankwah V, Quaicoe R, Adedia D.   +7 more
europepmc   +1 more source

Science Set Free: Open Access to research output [PDF]

, 2018
Van Nieuwerburgh, Inge
core   +1 more source

Agriculture versus fish – Norway in WTO [PDF]

The Norwegian agriculture is highly protected and subsidised. The opposite is the case for fisheries and fish farming which suffer from foreign market restrictions.
Gaasland, Ivar
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

El govern obert als nous estats digitals : quines biblioteques per a quina ciutadania?

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2019
Peña-López, Ismael
doaj   +1 more source

Recommendations for reporting regression-based norms and the development of free-access tools to implement them in practice. [PDF]

PLoS One
Blagus R, Leskošek B, Ortega FB, Tomkinson G, Jurak G.   +4 more
europepmc   +1 more source