Results 161 to 170 of about 8,461,599 (350)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

User-Centric Perspective in Random Access Cell-Free Aided by Spatial Separability [PDF]

, 2022
Victor Croisfelt, Taufik Abrão, José Carlos Marinello   +2 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Free access to medicines among older adults in primary care: a cross-sectional study. [PDF]

Sao Paulo Med J, 2020
Pinto IVL, Lima MG, Pantuzza LLN, Ceccato MDGB, Silveira MR, Reis AMM, Reis AMM.   +6 more
europepmc   +1 more source

When Is the Standard Analysis of Common Property Extraction under Free Access Correct? A Game-Theoretic Justification for Non-Game-Theoretic Analyses [PDF]

, 1995
Richard R. Brooks, J. Controneo, Michael P. Murray, Stephen W. Salant   +3 more
openalex  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

El gobierno abierto en los nuevos estados digitales : ¿qué bibliotecas para qué ciudadanía?

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2019
Peña-López, Ismael
doaj   +1 more source

Graph Neural Network Based Access Point Selection for Cell-Free Massive\n MIMO Systems [PDF]

, 2021
Vismika Ranasinghe, Nandana Rajatheva, Matti Latva‐aho   +2 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Do patients bypass primary care for common health problems under a free-access system? Experience of Taiwan. [PDF]

BMC Health Serv Res, 2020
Liang LL, Huang N, Shen YJ, Chen AY, Chou YJ.   +4 more
europepmc   +1 more source