Results 41 to 50 of about 19,018,457 (307)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Open access – ein Paradigmenwechsel für die öffentliche Bereitstellung von Wissen. Entwicklungen in Deutschland

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2007
The main characteristic of Open Access consists in making use of knowledge coming from the area of Education and Science: knowledge that has been made public and has been produced through public funding should be free (also in the sense of being free-of ...
Kuhlen, Rainer
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Open Access : India is moving towards Third world Superpower [PDF]

open access: yes, 2006
The past few years have seen tremendous developments in information production, acquisition, and dissemination. Budgetary restrictions in research libraries have led to a period known as the serial cutting era.
Hirwade, Mangala, Rajyalakshmi, D.
core   +1 more source

La Unió Europea com a cap i garant del sistema d'avaluació i difusió de la producció científica

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2019
Es presenta i es desenvolupa un sistema potencial d'avaluació i difusió de l'activitat científica generada a partir de recursos de finançament públics.
Caldera Serrano, Jorge
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

ACCESS TO PUBLIC INFORMATION AS A FUNDAMENTAL DEMOCRATIC RIGHT OF CITIZENS

open access: yesHorizons - International Scientific Journal
Countries that insist on development of a democratic society for freedom of information, that is, the right to access public documents. Only informed citizens are able to make correct decisions about each government and evaluate their work.
Svetlana Veljanovska
doaj   +1 more source

La Unión Europea como cabecera y garante del sistema de evaluación y difusión de la producción científica

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2019
Se presenta y desarrolla un potencial sistema de evaluación y difusión de la actividad científica generada a partir de recursos de financiación públicos.
Caldera Serrano, Jorge
doaj   +1 more source

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