Results 41 to 50 of about 2,120,300 (293)

Surveying and mapping a cave using 3d laser scanner: the open challenge with free and open source software [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2014
The present work is part of a series of activities involving different skills, in order to explore and document in detail one of the most visited caves in Liguria Region.
T. Cosso, I. Ferrando, A. Orlando
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Social justice and an information democracy with free and open source software [PDF]

open access: yes, 2011
This paper includes some thoughts on the implications of proprietary software versus free and open source software with regards to social justice, capital, and notions of an information society versus an information democracy.
Burns, Sean C.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Free and Open Source Software in Municipal Procurement:The Challenges and Benefits of Cooperation [PDF]

open access: yes, 2016
The use of free and open source software by municipal governments is the exception rather than the rule. This is due to a variety of factors, including a failure of many municipal procurement policies to take into account the benefits of free software ...
Colannino, Justin C.
core   +1 more source

Free and Open Source Software (FOSS)

open access: yes, 2020
This talk explores the history of open source software, its growth in use and some recent trends which threaten its long term stability. The original slides are available at https://niall-moran.gitlab.io/GOSW-FOSS/#/sec-title-slide Dr. Niall Moran is a research fellow at NUIG and senior computational scientist at ICHEC (Irish Centre for High End ...
openaire   +1 more source

Upgrade of foss date plug-in: Implementation of a new radargrammetric DSM generation capability [PDF]

open access: yes, 2016
Synthetic Aperture Radar (SAR) satellite systems may give important contribution in terms of Digital Surface Models (DSMs) generation considering their complete independence from logistic constraints on the ground and weather conditions. In recent years,
Crespi, Mattia Giovanni   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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