Results 61 to 70 of about 2,120,300 (293)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Free and Open Source Software in language mediator education:The MINTRAD Project

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research, 2013
The paper provides a description of the main objectives pursued and results obtained by the “Grupo de Estudos das Tecnoloxías Libres da Tradución (GETLT)”[1] during the implementation of the MINTRAD project focusing on the compilation of Free and Open ...
Marta Garcia-Gonzalez
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Free and open source cloud technology based on the type Software as a Service

open access: yesCTE Workshop Proceedings, 2017
The aim of this study is to design and implement the cloud computing technology with types of the services Software as a Service (SaaS). Objectives of the study is to analyze the free and open source cloud technology based on the type Software as a ...
Nataliya Mihailivna Kiyanovska
doaj   +1 more source

SPOT: Open Source framework for scientific data repository and interactive visualization [PDF]

open access: yes, 2018
SPOT is an open source and free visual data analytics tool for multi-dimensional data-sets. Its web-based interface allows a quick analysis of complex data interactively. The operations on data such as aggregation and filtering are implemented.
Attema, Jisk   +5 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Machine Learning Applied to the Field of Genomics

open access: yesApplied Medical Informatics, 2021
As the quantity and quality of genomic data increases and the computational tools and infrastructure become readily available, the new algorithms provide us with new insights in the field of genomics. Traditional machine learning algorithms proved useful
Simion Daniel TĂTAR, Gheorghe SEBESTYEN
doaj  

Free and Open Source Software (Foss) for Electronic Health Record Management in Developing Countries

open access: yesRwanda Medical Journal, 2013
An increasing number of open source projects over the past decade have found their way to the health sector, particularly in developing countries.Some of the more than 1,500 applications which have already been published in the public domain were ...
Marc Nyssen   +3 more
doaj   +1 more source

Perspectives on Free and Open Source Software [PDF]

open access: yes, 2005
What is the status of the Free and Open Source Software (F/OSS) revolution? Has the creation of software that can be freely used, modified, and redistributed transformed industry and society, as some predicted, or is this transformation still a work in progress?
openaire   +1 more source

Free and Open Source Software Licenses Explained [PDF]

open access: yesComputer, 2019
This installment of Computer's series exploring free and open source software confronts a pressing issue, free and open source software licenses: what they are, the rights they convey, and the restrictions they impose.
openaire   +1 more source

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