Results 81 to 90 of about 2,120,300 (293)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Copyright and Open Source Software Licensing [PDF]
, 2005 The open source software movement has swept the software industry by storm in recent times, challenging many pre-conceptions about existing software development and licensing models.
Chang, Sau Sheong
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
MATEC Web of Conferences, 2017 Pesticides are toxic chemicals aimed for the destroying pest on crops. Numerous data evidence about toxicity of pesticides on aquatic organisms. Since pesticides with similar properties tend to have similar biological activities, toxicity may be ...
Rastija Vesna +3 more
doaj +1 more source
Core-periphery communication and the success of free/libre open source software projects
Journal of Internet Services and Applications, 2017 We examine the relationship between communications by core and peripheral members and Free/Libre Open Source Software project success. The study uses data from 74 projects in the Apache Software Foundation Incubator.
Kevin Crowston, Ivan Shamshurin
doaj +1 more source
Punctuated Equilibrium in Software Evolution
, 2003 The approach based on paradigm of self-organized criticality proposed for experimental investigation and theoretical modelling of software evolution. The dynamics of modifications studied for three free, open source programs Mozilla, Free-BSD and Emacs ...
A. A. Gorshenev +9 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Journal of Internet Services and Applications, 2017 The license adopted by an open source software is associated with its success in terms of attractiveness and maintenance of an active ecosystem of users, bug reporters, developers, and sponsors because what can and cannot be done with the software and ...
Carlos Denner dos Santos
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source