Results 101 to 110 of about 1,970,658 (315)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters

open access: yesBMJ Open Respiratory Research
Introduction The emergence of new SARS-CoV-2 variants, capable of escaping the humoral immunity acquired by the available vaccines, together with waning immunity and vaccine hesitancy, challenges the efficacy of the vaccination strategy in fighting COVID-
Luiz Gustavo Teixeira Alves   +15 more
doaj   +1 more source

Social Representations of e-Mental Health Among the Actors of the Health Care System: Free-Association Study. [PDF]

open access: yesJMIR Ment Health, 2021
Morgiève M   +6 more
europepmc   +1 more source

'Dick Gregory's Food Run' through Columbus

open access: yes, 1976
A group of runners run down North High Street in Columbus, Ohio, with Dick Gregory (at center) in this photograph from the Columbus Free Press Association.
Gary Wilcox (Photographer); Columbus Free Press (Publisher)
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

NMA Newsletter; Newsletter - Newfoundland Medical Association

open access: yes, 1997
NLMA Communiqu, Volume 16, No. 4 (August/September 1997)The president reports -- 1997-98 Board of Directors -- Check out NLMA's homepage -- When organized medicine speaks its mind / Bruce Squires -- Good on ya, mate!
Newfoundland Medical Association
core  

Chinese Association of Greater Toledo newsletter, Special Publication, 2021

open access: yes, 2021
A newsletter published by the Chinese Association of Greater Toledo (CAGT). CAGT was founded in 1965 to support the Chinese community in and around Toledo, Ohio and uphold Chinese culture, language, and customs.
Chinese Association of Greater Toledo (Toledo, Ohio)
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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