Results 81 to 90 of about 6,112,486 (316)

Legal requirements for reporting clinical cases to the South African police or social services

South African Family Practice
Medical confidentiality is the cornerstone for a trustful relationship between patients and the health professionals attending to them. However, when history or clinical findings suggest certain offenses, statutory laws (Children’s Act, Older Persons Act,
Dirk T. Hagemeister, William Oosthuizen, Bridgette Mokae   +2 more
doaj   +1 more source

The Free Association Task: Proposal of a Clinical Tool for Detecting Differential Profiles of Semantic Impairment in Semantic Dementia and Alzheimer's Disease. [PDF]

Medicina (Kaunas), 2021
Zannino GD, Perri R, Marra C, Caruso G, Baroncini M, Caltagirone C, Carlesimo GA.   +6 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The effects of psychopathology and shame on social representations of health and lifestyle behaviours via free association: a graph analysis approach. [PDF]

BMC Psychol, 2021
Briseniou E, Skenteris N, Hatzoglou C, Tsitsas G, Diamantopoulos E, Dragioti E, Gouva M.   +6 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Analysis of English free association network reveals mechanisms of efficient solution of Remote Association Tests. [PDF]

PLoS One, 2021
Valba O, Gorsky A, Nechaev S, Tamm M.
europepmc   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Protective role of the HSP90 inhibitor, STA-9090, in lungs of SARS-CoV-2-infected Syrian golden hamsters

BMJ Open Respiratory Research
Introduction The emergence of new SARS-CoV-2 variants, capable of escaping the humoral immunity acquired by the available vaccines, together with waning immunity and vaccine hesitancy, challenges the efficacy of the vaccination strategy in fighting COVID-
Luiz Gustavo Teixeira Alves, Morris Baumgardt, Christine Langner, Mara Fischer, Julia Maria Adler, Judith Bushe, Theresa Catharina Firsching, Guido Mastrobuoni, Jenny Grobe, Katja Hoenzke, Stefan Kempa, Achim Dieter Gruber, Andreas Christian Hocke, Jakob Trimpert, Emanuel Wyler, Markus Landthaler   +15 more
doaj   +1 more source

Hicksville Union Free School District and Hicksville School Nurses Association [PDF]

, 2007
In the Matter of the Fact-Finding between THE BOARD OF EDUCATION OF THE HICKSVILLE UNION FREE SCHOOL DISTRICT and THE HICKSVILLE SCHOOL NURSES ASSOCIATION. PERB Case No: M 2005-264 Eugene S.
Ginsberg, Eugene S.
core   +1 more source