Results 131 to 140 of about 1,969,022 (331)

Inhomogeneous global minimizers to the one-phase free boundary problem

open access: hybrid, 2022
Daniela De Silva   +2 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

C-infinity interfaces of solutions for one-dimensional parabolic p-Laplacian equations

open access: yesElectronic Journal of Differential Equations, 1999
We study the regularity of a moving interface $x = zeta (t)$ of the solutions for the initial value problem $$ u_t = left(|u_x|^{p-2}u_x ight)_x quad u(x,0) =u_0 (x),, $$ where $u_0in L^1({Bbb R})$ and $p>2$.
Yoonmi Ham, Youngsang Ko
doaj  

Precipitate-Free Zones at the Grain Boundary of a Bicrystal of the Nickel-Base Superalloy Nimonic PE16

open access: hybrid, 1993
Harald Rösner   +3 more
openalex   +1 more source

Coercivity enhancement in heavy rare earth-free NdFeB magnets by grain boundary diffusion process [PDF]

open access: hybrid, 2018
Daniel Salazar   +4 more
openalex   +1 more source

Nonlocal Free Boundary Minimal Surfaces

open access: yes
We introduce the nonlocal analogue of the classical free boundary minimal hypersurfaces in an open domain $Ω$ of $\mathbb{R}^n$ as the (boundaries of) critical points of the fractional perimeter $\operatorname{Per}_s(\cdot,\,Ω)$ with respect to inner variations leaving $Ω$ invariant.
Badran, Marco   +2 more
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

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