Results 121 to 130 of about 4,837,642 (257)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Recommendations for execution of the changes in location of the Rio Grande stipulated in article I of the Boundary Treaty of 1970

, 1975
No ...
International Boundary and Water Commission
core  

Existence of Local Solutions to a Free Boundary Problem for Compressible Viscous Magnetohydrodynamics

Mathematics
The motion of viscous compressible magnetohydrodynamics (MHD) is considered in a domain bounded by a free boundary. The motion interacts through the free surface with an electromagnetic field located in a domain that is exterior to the free surface and ...
Wiesław J. Grygierzec, Wojciech M. Zaja̧czkowski   +1 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Global Regularity and Probabilistic Schemes for Free Boundary Surfaces of Multivariate American Derivatives and Their Greeks

, 2011
In a rather general setting of multivariate diffusion market models we derive global iterative probabilistic schemes for computing the free boundary and the Greeks for a generic class of American derivative models using front-fixing methods.
Jörg Kampen, Kampen, Jörg
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The structure of the free boundary in the fully nonlinear thin obstacle problem

, 2017
We study the regularity of the free boundary in the fully nonlinear thin obstacle problem. Our main result establishes that the free boundary is C1 near any regular point.
Ros-Oton, Xavier, Xavier Ros-Oton, Joaquim Serra, Serra, Joaquim   +3 more
core   +1 more source

Asymptotic behavior for a heat conduction problem with perfect-contact boundary condition

Electronic Journal of Differential Equations, 2003
In this paper we consider the heat conduction problem for a slab represented by the interval $[0,1]$. The initial temperature is a positive constant, the flux at the left end is also a positive constant, and at the right end there is a perfect contact ...
Andres Barrea, Cristina Turner
doaj  

A regularity result for incompressible elastodynamics equations in the ALE coordinates

Advanced Nonlinear Studies
We consider incompressible inviscid elastodynamics equations with a free surface and establish regularity of solutions for these equations. Compared with previous result on this free boundary problem [X. Gu and F.
Xie Binqiang
doaj   +1 more source