Results 121 to 130 of about 283,867 (316)
Free-Boundary Simulations of ITER Advanced Scenarios [PDF]
, 2013 Karim Besseghir
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
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MathematicsThe motion of viscous compressible magnetohydrodynamics (MHD) is considered in a domain bounded by a free boundary. The motion interacts through the free surface with an electromagnetic field located in a domain that is exterior to the free surface and ...
Wiesław J. Grygierzec +1 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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Asymptotic behavior for a heat conduction problem with perfect-contact boundary condition
Electronic Journal of Differential Equations, 2003 In this paper we consider the heat conduction problem for a slab represented by the interval $[0,1]$. The initial temperature is a positive constant, the flux at the left end is also a positive constant, and at the right end there is a perfect contact ...
Andres Barrea, Cristina Turner
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FREE-BOUNDARY SOLUTIONS FOR HIGH-BETA STELLARATORS OF LARGE ASPECT RATIO.
, 1969 F.L. Ribe
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Convergence of the discrete free boundaries for finite element approximations [PDF]
, 1983 Franco Brezzi, Luis Caffarelli
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
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A regularity result for incompressible elastodynamics equations in the ALE coordinates
Advanced Nonlinear StudiesWe consider incompressible inviscid elastodynamics equations with a free surface and establish regularity of solutions for these equations. Compared with previous result on this free boundary problem [X. Gu and F.
Xie Binqiang
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