Results 101 to 110 of about 4,837,642 (257)
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The impact factors of the risk index and diffusive dynamics of a SIS free boundary model. [PDF]
Tong Y, Ahn I, Lin Z.
europepmc +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Bifurcation analysis of a free boundary model of vascular tumor growth with a necrotic core and chemotaxis. [PDF]
Lu MJ, Hao W, Hu B, Li S.
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Series 7: Press releases [PDF]
Series consists of a number of press releases regarding the upcoming Boundary Centennial ...
core
C-infinity interfaces of solutions for one-dimensional parabolic p-Laplacian equations
We study the regularity of a moving interface $x = zeta (t)$ of the solutions for the initial value problem $$ u_t = left(|u_x|^{p-2}u_x ight)_x quad u(x,0) =u_0 (x),, $$ where $u_0in L^1({Bbb R})$ and $p>2$.
Yoonmi Ham, Youngsang Ko
doaj
On guaranteed control of the parabolic obstacle problem
The article deals with the study on the issue of guaranteed control of parabolic differential equations with constraints related to obstacles at the system level.
Olga A. Nikishina, Tatyana V. Pyatkova
doaj +1 more source
Free boundary methods and non-scattering phenomena. [PDF]
Salo M, Shahgholian H.
europepmc +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source

