Results 91 to 100 of about 4,837,642 (257)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Boundary-making in the public sphere: Contestations of free speech [PDF]

open access: yes, 2017
Freedom of speech is a fundamental human right and considered a core value in liberal democracies. However, it is also one of our time’s most contested issues, constantly claimed either to be too wide-ranging, allowing continuous repression of minority ...
Midtbøen, Arnfinn Haagensen   +2 more
core  

Free boundary dimers: random walk representation and scaling limit. [PDF]

open access: yesProbab Theory Relat Fields, 2023
Berestycki N, Lis M, Qian W.
europepmc   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Classical Bernoulli Type Free Boundary Problems [PDF]

open access: yes, 2019
Free boundary problems deal with solving partial differential equations (PDEs) in a domain, a part of whose boundary is prior unknown; that portion of the boundary is called a free boundary. Free boundary problems are widely used in various applications.
Aryal, Ashok, Dr.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Series 8: Plan [PDF]

open access: yes, 1947
Series consists of a plan for the celebration site of the Boundary ...

core  

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