Results 31 to 40 of about 64,698 (263)
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Existence of periodic solution to one dimensional free boundary problems for adsorption phenomena [PDF]
Известия Иркутского государственного университета: Серия "Математика", 2018 In this paper we consider a drying and wetting process in porous medium to create a mathematical model for concrete carbonation. The process is assumed to be characterized by the growth of the air zone and a diffusion of moisture in the air zone.
T. Aiki, N. Sato
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Analytic Approximation for American Straddle Options
Mathematics, 2022 This paper looks at adapting a recent approach found in the literature for pricing short-term American options to price American straddle options with two free boundaries.
Joanna Goard, Mohammed AbaOud
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Solution of the system of parametric equations of the sessile drop
Mathematical Modelling and Analysis, 2002 Several models of parameterization for the problem of free surface of the sessile liquid drop with nonlocal integral condition of prescribed volume are considered.
R. Ciupaila, M. Sapagovas
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Free boundary problems with Neuman boundary condition
Electronic Journal of Differential Equations, 2019 In this work, we study the continuity of a free boundary in a class of elliptic problems, with a Neuman boundary condition. The main idea is to use a change of variable that reduces the problem to the one studied in [16].
Abdeslem Lyaghfouri, Abderachid Saadi
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source