Results 91 to 100 of about 5,741,257 (294)

Reward Sensitivity Enhances Ventrolateral Prefrontal Cortex Activation During Free Choice

open access: yesFrontiers in Neuroscience, 2016
Expressing one’s preference via choice can be rewarding, particularly when decisions are voluntarily made as opposed to being forced. An open question is whether engaging in choices involving rewards recruits distinct neural systems as a function of ...
Catherine Cho   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

NARAL Steve O'Ban Birth Control Mailer

open access: yes, 2014
Mailer sent out making known the anti-choice rhetoric and anti-women stance of Steve O ...
NARAL Pro-Choice Washington
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

NARAL Flyer "Know the Facts: Misinformation in 12th & Delaware"

open access: yes, 2010
Literature that corrects misspoken facts by anti-choice protestors in the movie 12th ...
NARAL Pro-Choice America
core  

Choice-Induced Preference Change and Recollection of Choice in the Free-Choice Paradigm

open access: yesPsicológica
The choice-induced preference change (CIPC) effect observed in the free-choice paradigm (FCP) is hypothesized to be the result of cognitive dissonance reduction at revaluation.
Patrycja Didyk, Marek Nieznański
doaj   +1 more source

Species visitation at free‐choice quail feeders in west texas

open access: yesWildlife Society Bulletin, 2012
Providing supplemental feed is a common practice for the management of northern bobwhite (Colinus virginianus) and scaled quail (Callipepla squamata). The ecological efficacy and economic efficiency of a feeding program for quail can be evaluated using ...
Kelly D. Henson   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Free choice shapes normalized value signals in medial orbitofrontal cortex

open access: yesNature Communications, 2018
Neurons in prefrontal areas including the medial orbitofrontal cortex (mOFC) represent the relative reward value of choices. Here the authors report that mOFC neurons implement divisive normalization to encode the relative values of lottery options only ...
Hiroshi Yamada   +3 more
doaj   +1 more source

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