Results 81 to 90 of about 5,741,257 (294)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Conception of free will in the Christian-oriented psychology
Консультативная психология и психотерапия, 2010 The article provides a synthesis of the psychological concept of human will and ideas of free will in a Christian anthropology, and builds a united model of free will upon this base.
Mironova M.N.
doaj
Choice-induced preference change and the free-choice paradigm: A clarification [PDF]
Judgment and Decision Making, 2015 Positive spreading of ratings or rankings in the classical free-choice paradigm is commonly taken to indicate choice-induced change in preferences and has motivated influential theories as cognitive dissonance theory and self-perception theory.
Carlos Alós-Ferrer, Fei Shi
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Truth and consequence: a look behind the Vatican's ban on contraception
, 2008 With these words slamming the door on Catholics’use of modern contraceptives, Pope Paul VI cleaved the Catholic church into irreconcilable factions 40 years ago. The majority, unable to reconcile the rigid encyclical with their need for an updated sexual
Catholics for Choice
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Desperately seeking streaming: CHOICE digital consumers paying for content behaviour and attitudes
, 2015 Has the launch of new streaming services in Australia had an impact on the ways Australians access digital content or is a punitive regulatory approach necessary to reduce piracy?
Choice
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
NARAL Anti-Choice Scare Tactic Flyer
, 2017 Flyer denouncing anti-choice scare ...
NARAL Pro-Choice America
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