Results 161 to 170 of about 4,629,407 (316)
EasyCheck — Test Data for Free [PDF]
Jan Christiansen, Sebastian Fischer 0001
openaire +1 more source
THE ROLE OF DEPUTY PRINCIPALS IN MANAGING CONFLICT AMONG SECONDARY SCHOOL TEACHERS IN THE LEJWELEPUTSWA DISTRICT, IN THE FREE STATE PROVINCE [PDF]
Thesis (Phd. (Psychology of education )) - Central University of Technology, Free State, 2013This purpose of this study was to investigate the role of the deputy principals in managing conflict among secondary school teachers in the Lejweleputswa ...
Mphatsoe, Mantwa. Florence.
core
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Can Free AI Tools Replace Statistical Software in Data Analysis?
Artificial intelligence (AI) has become increasingly integrated into scientific publishing, performing a vast array of tasks for enhancing research efficiency, analysis, and dissemination [...]
Giuseppe Lippi
doaj +1 more source
A tool to assess the success of business intelligence implementation within Free State government departments : task technology fit perspective [PDF]
Thesis (Masters in Information Technology) -- Central University of Technology, Free State, 2019This study employed an information systems (IS) framework development based on a case study.
Moloabi, Tanki, Eusebia, Masekoala. +1 more
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Startups face critical challenges in prioritizing requirements under severe resource constraints. Although methods such as RICE and ICE are known, prior studies show that decisions often default to ad hoc judgments and stakeholder opinions.
Frédéric Pattyn +4 more
doaj +1 more source
A cost effective school management system for disadvantaged schools in the Free State province using the software as a service (SaaS) delivery model [PDF]
Thesis (M. Tech. (Information Technology)) -- Central University of technology, Free State, 2013The aim of this study was to create a dynamic software system that captures all information related to a student and delivers it to the educators, principal,
Kuriakose, Elizabeth B.
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source

