Results 171 to 180 of about 4,629,407 (316)

A Comparative study of marketing communications of local and foreign national small grocery tuck-shop owners in selected municipalities in the Free State Province [PDF]

open access: yes, 2018
Published ThesisDespite evidence of use and research in marketing communications by large retail businesses in South Africa, the continued proliferation of small grocery tuck-shops in South African townships has presented the small retail business ...
Phalatsi, Boitumelo Morakane Catherine
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Developing an induction and mentoring programme to assist newly appointed principals in selected education districts in the Free State province [PDF]

open access: yes, 2010
Thesis (Ph.D.) - Central University of Technology, Free State, 2010Newly appointed principals are facing enormous challenges as managers of their schools today.
Thobi, Lepono Desmond
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Label-free data standardization for clinical metabolomics. [PDF]

open access: yesBioData Min, 2017
Lokhov PG   +4 more
europepmc   +1 more source

ENGLISH AS THE LANGUAGE OF LEARNING FOR LIMITED ENGLISH PROFICIENCY GRADE 10 ACCOUNTING LEARNERS IN THE FREE STATE PROVINCE [PDF]

open access: yes, 2017
Published ThesisThe aim of this study is to investigate the effects of English as the language of learning for Limited English Proficiency (LEP) Grade 10 Accounting learners in Free State Province, identify the problems that influence learners’ learning ...
MODISE, MOTALENYANE ALFRED
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Synthesizer: Expediting synthesis studies from context-free data with information retrieval techniques. [PDF]

open access: yesPLoS One, 2017
Gandy LM   +9 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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