Results 61 to 70 of about 1,622,717 (242)
On Epistemics in Expected Free Energy for Linear Gaussian State Space Models
Entropy, 2021 Active Inference (AIF) is a framework that can be used both to describe information processing in naturally intelligent systems, such as the human brain, and to design synthetic intelligent systems (agents).
Magnus T. Koudahl +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Myth of objectivity and the origin of symbols
Frontiers in Sociology, 2023 An age-old challenge in epistemology and moral philosophy is whether objectivity exists independent of subjective perspective. Alfred North Whitehead labeled it a “fallacy of misplaced concreteness”; after all, knowledge is represented elusively in ...
Shagor Rahman
doaj +1 more source
Experiential fantasies, prediction, and enactive minds [PDF]
, 2015 A recent surge of work on prediction-driven processing models--based on Bayesian inference and representation-heavy models--suggests that the material basis of conscious experience is inferentially secluded and neurocentrically ...
Kirchhoff, Michael David
core
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
A Factor Graph Description of Deep Temporal Active Inference
Frontiers in Computational Neuroscience, 2017 Active inference is a corollary of the Free Energy Principle that prescribes how self-organizing biological agents interact with their environment. The study of active inference processes relies on the definition of a generative probabilistic model and a
Bert de Vries +2 more
doaj +1 more source
Quenched Point-to-Point Free Energy for Random Walks in Random Potentials [PDF]
, 2013 We consider a random walk in a random potential on a square lattice of arbitrary dimension. The potential is a function of an ergodic environment and some steps of the walk.
Rassoul-Agha, Firas, Seppäläinen, Timo
core
, 2005 Based on a rigorous extension of classical statistical mechanics to networks, we study a specific microscopic network Hamiltonian. The form of this Hamiltonian is derived from the assumption that individual nodes increase/decrease their utility by ...
Christoly Biely +6 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source