Results 81 to 90 of about 9,681,538 (276)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
‘Between righteousness and alms’ in Tobit: What was the author’s real intention?
HTS Teologiese Studies/Theological Studies, 2020 Before the Semitic fragments of 4QTobit were found at Qumran, the 4th-century Greek GI version of Tobit was thought to be original and was regarded as ‘a lesson on almsgiving and its redeeming powers’. In his presentation of the 4Q196–4Q199 (Aramaic) and
Annette H. Evans
doaj +1 more source
Rocky Mountain Journal of Mathematics, 2002 An Abelian group \(A\) is \(M\)-free with basis \(X\) if \(X\) is a subset of \(A\) such that every map from \(X\) to the Abelian group \(M\) extends uniquely to a homomorphism from \(A\) to \(M\). Examples are split-\(M\)-free groups which are direct sums of the free group with basis \(X\) and a group which has only the zero homomorphism into \(M ...
Dugas, Manfred +2 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
MATHEMATICA SCANDINAVICA, 1994 The authors investigates the free archimedean (abelian) \(\ell\)-group generated by a po-group \([G,P]\) \((P= \{x\in G\): \(x\geq 0\})\). Main results: 1. There exists an archimedean free \(\ell\)-group generated by a po-group \([G,P]\) if and only if \([G,P]\) is a po-group isomorphic to an archimedean \(\ell\)-group. 2.
Ton, Dao-Rong, He, Kai-Yao
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Intuitionistic Free Abelian Groups
Mathematical Logic Quarterly, 1988 The paper provides an intuitionistic construction of free abelian groups over arbitrary sets. It shows that a subgroup of a free abelian group is not necessarily itself free abelian, and that \(''free=projective''\Rightarrow full\) AC, for abelian groups. The paper uses Kripke models. The second part deals with the conditions for admitting an apartness
Dalen, D. van, Vries, F.-J. de
openaire +3 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Interpolated free group factors [PDF]
Pacific Journal of Mathematics, 1994 8 pages, AMSTeX 2.1, KD-at-UCB ...
openaire +4 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source