Results 71 to 80 of about 7,806,666 (239)
On some groups whose subnormal subgroups are contranormal-free [PDF]
International Journal of Group TheoryIf $G$ is a group, a subgroup $H$ of $G$ is said to be contranormal in $G$ if $H^G = G$, where $H^G$ is the normal closure of $H$ in $G$. We say that a group is contranormal-free if it does not contain proper contranormal subgroups.
Leonid Kurdachenko +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Stretching One’s Legs: Free Word-Groups vs Idioms [PDF]
Ученые записки Казанского университета: Серия Гуманитарные науки, 2016 The article deals with a corpus-based case study of two somatic/gesture/movement idioms containing the constituent legs, namely Russian protânut’ nogi (to die) and English to stretch one’s legs (to walk around and loosen one’s leg muscles after sitting ...
P.S. Dronov
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Relative outer automorphisms of free groups [PDF]
, 2011 Let $A_1,...,A_k$ be a system of free factors of $F_n$. The group of relative automorphisms $Aut(F_n;A_1,...,A_k)$ is the group given by the automorphisms of $F_n$ that restricted to each $A_i$ are conjugations by elements in $F_n$. The group of relative
Meucci, Erika
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Embeddings and chains of free groups [PDF]
, 2008 We build two non-abelian CSA-groups in which maximal abelian subgroups are conjugate and ...
Jaligot, Eric, Neman, Azadeh
core +3 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source