Results 31 to 40 of about 6,096 (252)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Features of Discourse Presentation in Translation: Literary and Narratological Insights into Translation Universals

open access: yesInternational Journal of Literary Linguistics, 2016
Several translation scholars have recognised translation as a form of discourse mediation or discourse presentation (see, for example, Mossop 1998).
Päivi Kuusi
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Michael Toolan, Progressione narrativa nel racconto: primi passi in una stilistica dei corpora

open access: yesEnthymema, 2010
Using tools derived from corpus linguistics, Toolan proposes some principles and techniques for a stylistic analysis which aims at the detection of textual elements that are responsible for reader's expectations and narrative prospection.
Federico Pianzola
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Use of Free Indirect Discourse in J. R. Ward’s Black Dagger Brotherhood series

open access: yesColloquy: Text, Theory, Critique, 2019
Although the romance genre has received a lot of attention in feminist and gender studies, particularly in the 1970s and 1980s, it is still largely ignored by narratologists and other literary theorists.
Evie Kendal
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Traversing the speech and thought presentation features of Merlinda Bobis’s “The Sadness Collector” [PDF]

open access: yesAsian Journal of English Language Studies (AJELS), 2013
This study aims to describe the effects of stylistic features in extrapolating the meaning and sociocultural realm of Merlinda Bobis’s short story, “The Sadness Collector.” The story’s theme, the breakdown of a family brought about by migration, is ...
Rachelle B. Lintao
doaj  

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