Results 31 to 40 of about 14,326 (251)

Types of speech in the novel Mitrova Amerika by Petar Sarić [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini, 2019
The subject of this paper are different types of speech in the novel Mitrova Amerika written by Petar Sarić, a distinguished writer from Kosovo and Metohija.
Redžić Emilija D.
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Faire entendre la racialisation dans Écrits pour la parole de Léonora Miano

open access: yesItinéraires, 2022
In Écrits pour la parole, Léonora Miano gives a voice to the racialized people living in France. I will study how race gives shape to texts. I will see that Miano writes about the difficulty of speaking about race, by playing with the fragmenting of ...
Marion Coste
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Free Indirect Discourse. German and Russian Literature

open access: yesEnthymema
The paper first gives a definition of free indirect discourse (FID) and then characterizes the two main directions of its research. The more traditional one, is based on the application of the three modes of speech representation to the representation ...
Wolf Schmid
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Potential of Using Formalized Parameters for Modeling Speech Action

open access: yesНаучный диалог, 2021
The quantitative parameters characterizing direct and indirect connections of words in the composition of the associative field “polite” are studied on the basis of the “Project of a multilingual associative thesaurus of politeness”. The aim of the study
N. I. Stepykin
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy