Results 181 to 190 of about 166,193,329 (284)

Geopolitics and public health: Europe under the shadow of the U.S. National Security Strategy. [PDF]

Lancet Reg Health Eur
Cylus J, McKee M.
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Potential entry pathways for 25 vector-borne disease agents. [PDF]

EFSA J
European Food Safety Authority (EFSA), Dhollander S, Baltusyte I, Bigoni F, Broglia A, Figuerola J, Thulke HH, Chueca Miranda MA.   +7 more
europepmc   +1 more source

Neurological, Neurodevelopmental and Treatment Outcomes in Patients With Pyruvate Dehydrogenase Complex Deficiency

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of this study was to characterize intellectual and motor function, neurological features including epilepsy, treatment response, and adaptive behavior in patients with pyruvate dehydrogenase complex deficiency (PDCD) in Sweden.
Antri Savvidou, Colin Reilly, Kalliopi Sofou, Sofia Ygberg, Erik A. Eklund, Karin Naess, Niklas Darin   +6 more
wiley   +1 more source

Section 17 of the Finnish Alcohol Act and the free movement of goods

This Bachelor's thesis examines Section 17 of the Finnish Alcohol Act in the light of free movement of goods within the EU internal market. Amendment of Section 17 of the Alcohol Act is the latest amendment to Finnish alcohol legislation and the topic ...
Väyrynen, Karri
core  

Spreading potential in disease relevant networks: Predicting centralities in rural Northeast Madagascar. [PDF]

PLOS Glob Public Health
DeSisto CMM, Binder RA, Kauffman K, Barrett TM, Pender M, Kramer RA, Soarimalala V, Rabezara JY, Rahary P, Moody J, Nunn CL.   +10 more
europepmc   +1 more source

Open border ecosystems: Against globalised laissez-faire conservation. [PDF]

Camb Prism Extinct
Lean CH.
europepmc   +1 more source

Early Clinical and Cerebrospinal Fluid Predictors of 1‐Year Recurrence in Autoimmune GFAP Astrocytopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A) is an inflammatory central nervous system disorder with variable outcomes. Relapse occurs in a subset of patients, but early predictors remain unclear. We aimed to identify admission‐available features associated with 1‐year recurrence and develop an interpretable ...
Qingting Hong, Yuping Xiao, Yuhan Wu, Ziyuan Huang, Weishan Liang, Li Xiao, Yaqing Shu, Tingting Lu, Yanyu Chang, Wei Qiu, Yuge Wang   +10 more
wiley   +1 more source

Regulation of the veterinary profession: the authorization to practice, origins, milestones, and emerging challenges. [PDF]

Front Vet Sci
Vaarten J, De Briyne N, van Herten J, De Vliegher S.   +3 more
europepmc   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source