Results 121 to 130 of about 1,418,478 (304)

Biological control of stored-product insects in commodities, food processing facilities and museums

open access: yes, 2010
Non-chemical control methods have gained importance in integrated pest management, as policies aiming to minimize the application of residual chemical insecticides are being adopted by many companies, and a growing market of organic produce.
Schöller, Matthias, Schöller, M.
core   +2 more sources

Stability of Cauchy–Stieltjes Kernel Families by Free and Boolean Convolutions Product

open access: yesMathematics
Let F(νj)={Qmjνj,mj∈(m−νj,m+νj)}, j=1,2, be two Cauchy–Stieltjes Kernel (CSK) families induced by non-degenerate compactly supported probability measures ν1 and ν2. Introduce the set of measures F=F(ν1)⊞F(ν2)={Qm1ν1⊞Qm2ν2,m1∈(m−ν1,m+ν1)andm2∈(m−ν2,m+ν2)}.
Ayed. R. A. Alanzi   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Web-enabled and Tether-Free Augmented Modeling and Simulation Technologies

open access: yes, 2002
This paper addresses the innovation needs in using web-enabled and tether-free technologies to augment modeling and simulation for nextgeneration product design, manufacturing, and services.
Jay Lee, For Next-Generation Product
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Corporate Leverage and Product Differentiation Strategy [PDF]

open access: yes
We explore the joint determination of product differentiation strategy and corporate leverage in a setting where (i) product differentiation is valued by customers; (ii) debt is necessary to discipline managers; and (iii) liquidation is costly for ...
Stefan ARPING, Gyöngyi LÓRÁNTH
core  

Generalizations of Product-Free Subsets

open access: yes, 2009
In this paper, we present some generalizations of Gowers’s result about product-free subsets of groups. For any group G of order n, a subset A of G is said to be product-free if there is no solution of the equation ab = c with a, b, c Epsilon A ...
Kiran S. Kedlaya   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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