Results 91 to 100 of about 7,348 (250)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Counting markedness : a corpus investigation on German free relative constructions
, 2004 This paper reports the results of a corpus investigation on case conflicts in German argument free relative constructions. We investigate how corpus frequencies reflect the relative markedness of free relative and correlative constructions, the relative ...
Zugck, Marco, Vogel, Ralf
core
Cross-linguistic variation in modality systems: The role of mood
Semantics and Pragmatics, 2010 The St'át'imcets (Lillooet Salish) subjunctive mood appears in nine distinct environments, with a range of semantic effects, including weakening an imperative to a polite request, turning a question into an uncertainty statement, and creating an ...
Lisa Matthewson
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Brain structural and functional correlates of resilience to Bipolar Disorder
Frontiers in Human Neuroscience, 2012 Background: Resilient adaptation can be construed in different ways, but as used here it refers to the adaptive brain changes associated with avoidance of psychopathology despite familiar risk for Bipolar Disorder (BD).
Sophia eFrangou
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Transparent free relatives in English
, 2008 Transparent free relatives (TFRs) are constituents involving a WH-gap dependency in which the phrase that is predicated of the gap associated with \u27what\u27, not the wh-phrase itself, functions as the syntactic and semantic "nucleus." Previous ...
Yoo, Eun-Jung
core +1 more source
The Automorphism Groups of Relatively Free Algebras
Journal of Algebra, 1998 The authors study the automorphisms groups of relatively free algebras having in mind the automorphism groups of relatively free groups. They saw that the results can be formulated by considering relatively free algebras of infinite rank. So let \(\Omega\) be an operator domain. An \(\Omega\)-algebra is a set \(G\) in which for every \(\omega\in\Omega\)
Bryant, R. M., Roman'kov, V. A.
openaire +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source